Long-chain fatty acyl-CoA esters are key intermediates in numerous lipid metabolic
pathways, and recognized as important cellular signaling molecules. The intracellular flux …

The existence of specific binding sites for benzodiazepines (BZs) in the brain has prompted
the search for endogenous BZ receptor ligands designated by the generic term …

Dietary supplementation of glutamine prevents intestinal dysfunction and atrophy in
weanling piglets, but the underlying mechanism (s) are largely unknown. This study was …

Neurosteroids are neuroactive brain-born steroids. They can act through non-genomic
and/or through genomic pathways. Genomic pathways are largely described for steroid …

Besides serving as essential substrates for β-oxidation and synthesis of triacylglycerols and
more complex lipids like sphingolipids and sterol esters, long-chain fatty acyl-CoA esters are …

Benzodiazepine receptors are expressed very early in the brain during embryonic life,
suggesting that endogenous ligands for these receptors may play an important role during …

Pancreatic secretion is regulated by highly integrated neural and hormonal influences that
involve the brain, enteric nervous system, and gastrointestinal tract. Although these …

Pancreatic proteases in the duodenum inhibit the release of cholecystokinin (CCK) and thus
exert feedback control of pancreatic exocrine secretion. Exclusion of proteases from the …

The octadecaneuropeptide ODN (QATVGDVNTDRPGLLDLK), originally characterized as
an endogenous ligand for central-type benzodiazepine receptors, increases intracellular …

Background & Aims: Guanylin activates an intestinal guanylate cyclase (GCC) and
stimulates electrolyte movement across the gut epithelium. Cells expressing guanylin …