Almost all Glioblastoma (GBM) are either intrinsically resistant to the chemotherapeutical
drug temozolomide (TMZ) or acquire therapy-induced mutations that cause …

Mann and Zhang et al. developed a robust ex vivo slice culture platform consisting of
resected patient high-and low-grade glioma tissue engrafted onto rat organotypic brain …

Transdifferentiation (TD), a somatic cell reprogramming process that eliminates pluripotent
intermediates, creates cells that are ideal for personalized anti-cancer therapy. Here, we …

The lack of functional precision models that recapitulate the pathology and structure/function
relationship of advanced ovarian cancer (OC) within an appropriate anatomic setting …

Pediatric low-grade gliomas (pLGGs) are the most common primary brain tumors in children
and are almost exclusively driven by alterations in the mitogen-activated protein kinase …