Bacteria must maintain the ability to modify and repair the peptidoglycan layer without
jeopardising its essential functions in cell shape, cellular integrity and intermolecular …

Most bacteria divide through a highly conserved process called binary fission, in which there
is symmetric growth of daughter cells and the synthesis of peptidoglycan at the mid-cell to …

Peptidoglycan (PG) is an essential structural component of the bacterial cell wall that is
synthetized during cell division and elongation. PG forms an extracellular polymer crucial for …

Bacterial cell wall formation is essential for cellular survival and morphogenesis. The
peptidoglycan (PG), a heteropolymer that surrounds the bacterial membrane, is a key …

Bacteria in general serve two main tasks: cell growth and division. Both processes include
peptidoglycan extension to allow cell expansion and to form the poles of the daughter cells …

Peptidoglycan (PG) is a central component of the bacterial cell wall, and the disruption of its
biosynthetic pathway has been a successful antibacterial strategy for decades. PG …

Due to the rising incidence of antibiotic-resistant infections, the last-line antibiotics,
polymyxins, have resurged in the clinics in parallel with new bacterial strategies of escape …

The surge of antimicrobial resistance threatens efficacy of current antibiotics, particularly
against Pseudomonas aeruginosa, a highly resistant gram-negative pathogen. The …

Antimicrobial resistance (AMR) in bacterial pathogens is a worldwide health issue. The
innovation gap in discovering new antibiotics has remained a significant hurdle in …

Background: Sulfate-reducing bacteria (SRB) reduce sulfate to yield H2S and are commonly
found in the human gut. Excess H2S has been linked to gut inflammation and is implicated …