Effects of exercise training on the autonomic nervous system with a focus on anti-inflammatory and antioxidants effects

M Daniela, L Catalina, O Ilie, M Paula, I Daniel-Andrei… - Antioxidants, 2022 - mdpi.com
Studies show that the autonomic nervous system (ANS) has an important impact on health in
general. In response to environmental demands, homeostatic processes are often …

Characterization and modulation of systemic inflammatory response to exhaustive exercise in relation to oxidative stress

K Suzuki, T Tominaga, RT Ruhee, S Ma - Antioxidants, 2020 - mdpi.com
Exhaustive exercise induces systemic inflammatory responses, which are associated with
exercise-induced tissue/organ damage, but the sources and triggers are not fully …

The integrative role of sulforaphane in preventing inflammation, oxidative stress and fatigue: A review of a potential protective phytochemical

RT Ruhee, K Suzuki - Antioxidants, 2020 - mdpi.com
Cruciferous vegetables hold a myriad of bioactive molecules that are renowned for
possessing unique medicinal benefits. Sulforaphane (SFN) is one of the potential …

Naturally derived heme-oxygenase 1 inducers and their therapeutic application to immune-mediated diseases

SC Funes, M Rios, A Fernández-Fierro… - Frontiers in …, 2020 - frontiersin.org
Heme oxygenase (HO) is the primary antioxidant enzyme involved in heme group
degradation. A variety of stimuli triggers the expression of the inducible HO-1 isoform, which …

Sulfur compounds: From plants to humans and their role in chronic disease prevention

CR Hill, A Shafaei, L Balmer, JR Lewis… - Critical Reviews in …, 2023 - Taylor & Francis
Sulfur is essential for the health of plants and is an indispensable dietary component for
human health and disease prevention. Its incorporation into our food supply is heavily reliant …

Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde …

K Ishida, K Kaji, S Sato, H Ogawa, H Takagi… - The Journal of nutritional …, 2021 - Elsevier
Alcoholic liver disease (ALD)-related fibrosis results from a variety of mechanisms including
the accumulation of acetaldehyde, reactive oxygen species, and hepatic overload of …

Organosulfur compounds: A review of their anti-inflammatory effects in human health

RT Ruhee, LA Roberts, S Ma, K Suzuki - Frontiers in nutrition, 2020 - frontiersin.org
Phytonutrients are widely recognized for providing protective human health benefits. Among
the phytonutrients, epidemiological and experimental studies show that dietary organosulfur …

Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein

J Gasparello, E D'Aversa, C Papi, L Gambari, B Grigolo… - Phytomedicine, 2021 - Elsevier
Background A key clinical feature of COVID-19 is a deep inflammatory state known as
“cytokine storm” and characterized by high expression of several cytokines, chemokines and …

Protective effects of sulforaphane on exercise-induced organ damage via inducing antioxidant defense responses

RT Ruhee, S Ma, K Suzuki - Antioxidants, 2020 - mdpi.com
Regular exercise is beneficial to maintain a healthy lifestyle, but the beneficial effects are
lost in the case of acute exhaustive exercise; this causes significant inflammation, oxidative …

Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophages

S Bahiraii, M Brenner, F Yan, W Weckwerth… - Frontiers in …, 2022 - frontiersin.org
Murine macrophages activated by the Toll-like receptor 4 agonist lipopolysaccharide (LPS)
polarize to the M1 type by inducing proinflammatory marker proteins and changing their …