Postpartum involution and cancer: an opportunity for targeted breast cancer prevention and treatments?

VF Borges, TR Lyons, D Germain, P Schedin - Cancer research, 2020 - AACR
Childbirth at any age confers a transient increased risk for breast cancer in the first decade
postpartum and this window of adverse effect extends over two decades in women with late …

Relationships between breast feeding and breast cancer subtypes: lessons learned from studies in humans and in mice

CB Ambrosone, MJ Higgins - Cancer research, 2020 - AACR
There are differential risk relationships between parity and breast cancer according to
estrogen receptor (ER) status, with an increased risk of ER− disease reduced by …

Young-onset breast cancer outcomes by time since recent childbirth in Utah

Z Zhang, S Bassale, S Jindal, A Fraser… - JAMA Network …, 2022 - jamanetwork.com
Importance Breast cancer diagnosed within 5 to 10 years after childbirth, calledpostpartum
breast cancer (PPBC), is associated with increased risk for metastasis and death. Whether a …

Semaphorin 7A promotes macrophage-mediated lymphatic remodeling during postpartum mammary gland involution and in breast cancer

AM Elder, BAJ Tamburini, LS Crump, SA Black… - Cancer research, 2018 - AACR
Postpartum mammary gland involution is a tissue remodeling event that occurs in all
mammals in the absence of nursing or after weaning to return the gland to the pre-pregnant …

Inflammatory breast cancer: unique biological and therapeutic considerations

WA Woodward - The Lancet Oncology, 2015 - thelancet.com
Through the concerted efforts of many patients, health-care providers, legislators, and other
supporters, the past decade has seen the development of the first clinics dedicated to the …

Postpartum breast cancer: mechanisms underlying its worse prognosis, treatment implications, and fertility preservation

H Lefrère, L Lenaerts, VF Borges, P Schedin… - International Journal of …, 2021 - ijgc.bmj.com
Breast cancers that occur in young women up to 5 to 10 years' postpartum are associated
with an increased risk for metastasis and death compared with breast cancers diagnosed in …

Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes

S Jindal, ND Pennock, D Sun, W Horton… - Nature …, 2021 - nature.com
Young women's breast cancer (YWBC) has poor prognosis and known interactions with
parity. Women diagnosed within 5–10 years of childbirth, defined as postpartum breast …

Predictors of mammographic microcalcifications

S Azam, M Eriksson, A Sjölander… - … journal of cancer, 2021 - Wiley Online Library
We examined the association between established risk factors for breast cancer and
microcalcification clusters and their asymmetry. A cohort study of 53 273 Swedish women …

CCL8 promotes postpartum breast cancer by recruiting M2 macrophages

E Farmaki, V Kaza, I Chatzistamou, H Kiaris - Iscience, 2020 - cell.com
The microenvironment of postpartum mammary gland promotes tumor growth and
metastasis in animal models and is linked to increased risk of breast cancer and poor …

miR-335-5p targets SDC1 to regulate the progression of breast cancer

G Song, Y Ma, Y Ma, P Liu, L Hou, Z Xu… - Critical Reviews™ in …, 2022 - dl.begellhouse.com
The objective of the study was to explore the role of SDC1 in breast cancer cells. Our study
also investigated the regulatory relationship between SDC1 and the microRNA (miRNA) …