[HTML][HTML] Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics

P Mi - Theranostics, 2020 - ncbi.nlm.nih.gov
In recent years, much progress has been motivated in stimuli-responsive nanocarriers,
which could response to the intrinsic physicochemical and pathological factors in diseased …

Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation

J Li, K Kataoka - Journal of the American Chemical Society, 2020 - ACS Publications
The past few decades have witnessed an evolution of nanomedicine from biologically inert
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …

An Adenosine Triphosphate-Responsive Autocatalytic Fenton Nanoparticle for Tumor Ablation with Self-Supplied H2O2 and Acceleration of Fe(III)/Fe(II) Conversion

L Zhang, SS Wan, CX Li, L Xu, H Cheng, XZ Zhang - Nano Letters, 2018 - ACS Publications
Chemodynamic therapy (CDT) can efficiently destroy tumor cells via Fenton reaction in the
presence of H2O2 and a robust catalyst. However, it has faced severe challenges including …

ROS‐responsive polyprodrug nanoparticles for triggered drug delivery and effective cancer therapy

X Xu, PE Saw, W Tao, Y Li, X Ji, S Bhasin… - Advanced …, 2017 - Wiley Online Library
The application of nanoparticles (NPs) to drug delivery has led to the development of novel
nanotherapeutics for the treatment of various diseases including cancer. However, clinical …

Enhanced antitumor efficacy by a cascade of reactive oxygen species generation and drug release

S Wang, G Yu, Z Wang, O Jacobson, LS Lin… - Angewandte …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) can be used not only as a therapeutic agent for
chemodynamic therapy (CDT), but also as a stimulus to activate release of antitumor drugs …

Tumor‐specific drug release and reactive oxygen species generation for cancer chemo/chemodynamic combination therapy

S Wang, Z Wang, G Yu, Z Zhou, O Jacobson… - Advanced …, 2019 - Wiley Online Library
The combination of chemotherapeutic drugs and reactive oxygen species (ROS) is a
promising strategy to achieve improved anticancer effect. Herein, a nanomedicine …

[HTML][HTML] Polymeric micellar systems—a special emphasis on “smart” drug delivery

I Negut, B Bita - Pharmaceutics, 2023 - mdpi.com
Concurrent developments in anticancer nanotechnological treatments have been observed
as the burden of cancer increases every year. The 21st century has seen a transformation in …

Controlling the biodistribution and clearance of nanomedicines

H Cabral, J Li, K Miyata, K Kataoka - Nature Reviews Bioengineering, 2024 - nature.com
Nanomedicines improve drug bioavailability, the dose–response relationship, targeting
ability, efficacy and safety compared to conventional freely administered drugs …

Nanoplatform-based cascade engineering for cancer therapy

J Chen, Y Zhu, C Wu, J Shi - Chemical Society Reviews, 2020 - pubs.rsc.org
Various therapeutic techniques have been studied for treating cancer precisely and
effectively, such as targeted drug delivery, phototherapy, tumor-specific catalytic therapy …

Stimulus-cleavable chemistry in the field of controlled drug delivery

Y Xue, H Bai, B Peng, B Fang, J Baell, L Li… - Chemical Society …, 2021 - pubs.rsc.org
Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …