Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Innate lymphoid cells in the initiation, regulation and resolution of inflammation

GF Sonnenberg, D Artis - Nature medicine, 2015 - nature.com
A previously unappreciated cell type of the innate immune system, termed innate lymphoid
cells (ILCs), has been characterized in mice and humans and found to influence the …

Therapeutic opportunities of the IL-22–IL-22R1 system

R Sabat, W Ouyang, K Wolk - Nature reviews Drug discovery, 2014 - nature.com
Abstract Interleukin-22 (IL-22) is a key effector molecule that is produced by activated T cells,
including T helper 22 (TH22) cells, TH17 cells and TH1 cells, as well as subsets of innate …

HIV‐associated chronic immune activation

M Paiardini, M Müller‐Trutwin - Immunological reviews, 2013 - Wiley Online Library
Systemic chronic immune activation is considered today as the driving force of CD 4+ T‐cell
depletion and acquired immunodeficiency syndrome (AIDS). A residual chronic immune …

Microbial translocation in the pathogenesis of HIV infection and AIDS

G Marchetti, C Tincati, G Silvestri - Clinical microbiology reviews, 2013 - Am Soc Microbiol
In pathogenic simian immunodeficiency virus (SIV) and human immunodeficiency virus
(HIV) infections, the translocation of microbial products from the gastrointestinal (GI) tract to …

Immune activation and HIV persistence: implications for curative approaches to HIV infection

NR Klatt, N Chomont, DC Douek… - Immunological …, 2013 - Wiley Online Library
Despite complete or near‐complete suppression of human immunodeficiency virus (HIV)
replication with combination antiretroviral therapy, both HIV and chronic …

IL-17 in the pathogenesis of disease: good intentions gone awry

S Majumder, MJ McGeachy - Annual review of immunology, 2021 - annualreviews.org
The IL-17 family is an evolutionarily old cytokine family consisting of six members (IL-17A
through IL-17F). IL-17 family cytokines signal through heterodimeric receptors that include …

Microbial translocation and microbiome dysbiosis in HIV-associated immune activation

AS Zevin, L McKinnon, A Burgener… - Current Opinion in HIV …, 2016 - journals.lww.com
Microbial translocation and microbiome dysbiosis in HIV-asso... : Current Opinion in HIV and
AIDS Microbial translocation and microbiome dysbiosis in HIV-associated immune activation …

Microbial translocation, immune activation, and HIV disease

NR Klatt, NT Funderburg, JM Brenchley - Trends in microbiology, 2013 - cell.com
The advent of combination antiretroviral therapy (cART) has significantly improved the
prognosis of human immunodeficiency virus (HIV)-infected individuals. However, individuals …

Residual immune dysregulation syndrome in treated HIV infection

MM Lederman, NT Funderburg, RP Sekaly… - Advances in …, 2013 - Elsevier
Antiretroviral therapy has revolutionized the course of HIV infection, improving immune
function and decreasing dramatically the mortality and morbidity due to the opportunistic …