Most studies in the field of ecology and evolution aiming to connect genotype to phenotype
rarely validate identified loci using functional tools. Recent developments in RNA …

The long-term survival of any multicellular species depends on the success of its germline in
producing high-quality gametes and maximizing survival of the offspring. Studies in …

The regulation of mRNA translation, both globally and at the level of individual transcripts,
plays a central role in the development and function of germ cells across species. Genetic …

Although asexual lineages evolved from sexual lineages in many different taxa, the genetics
of sex loss remains poorly understood. We addressed this issue in the pea aphid …

Being relatively simple and practical, Drosophila transgenic RNAi is the technique of top
priority choice to quickly study genes with pleiotropic functions. However, drawbacks have …

Males and females typically pursue divergent reproductive strategies and accordingly
require different dietary compositions to maximise their fitness. Here we move from …

The asymmetric division of adult stem cells into one self-renewing stem cell and one
differentiating cell is critical for maintaining homeostasis in many tissues. One paradigmatic …

Germline stem cells divide asymmetrically to produce one new daughter stem cell and one
daughter cell that will subsequently undergo meiosis and differentiate to generate the …

Spermatogenesis is a dynamic developmental process requiring precisely timed transitions
between discrete stages. Specifically, the germline undergoes three transitions: from mitotic …

Accumulation of toxic proteins in neurons has been linked with the onset of
neurodegenerative diseases, which in many cases are characterized by altered neuronal …