Reelin and neuropsychiatric disorders

K Ishii, K Kubo, K Nakajima - Frontiers in cellular neuroscience, 2016 - frontiersin.org
Proper neuronal migration and laminar formation during corticogenesis is essential for
normal brain function. Disruption of these developmental processes is thought to be …

Neuronal migration mechanisms in development and disease

M Valiente, O Marín - Current opinion in neurobiology, 2010 - Elsevier
Neuronal migration is a fundamental process that determines the final allocation of neurons
in the nervous system, establishing the basis for the subsequent wiring of neural circuitry …

Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex

SJ Franco, I Martinez-Garay, C Gil-Sanz… - Neuron, 2011 - cell.com
Neuronal migration is critical for establishing neocortical cell layers and migration defects
can cause neurological and psychiatric diseases. Recent studies show that radially …

[HTML][HTML] Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1

K Sekine, T Kawauchi, K Kubo, T Honda, J Herz… - Neuron, 2012 - cell.com
Birthdate-dependent neuronal layering is fundamental to neocortical functions. The
extracellular protein Reelin is essential for the establishment of the eventual neuronal …

Cobblestone lissencephaly: neuropathological subtypes and correlations with genes of dystroglycanopathies

L Devisme, C Bouchet, M Gonzalès, E Alanio, A Bazin… - Brain, 2012 - academic.oup.com
Cobblestone lissencephaly represents a peculiar brain malformation with characteristic
radiological anomalies, defined as cortical dysplasia combined with dysmyelination …

The role of Rho GTPase proteins in CNS neuronal migration

EE Govek, ME Hatten… - Developmental …, 2011 - Wiley Online Library
The architectonics of the mammalian brain arise from a remarkable range of directed cell
migrations, which orchestrate the emergence of cortical neuronal layers and pattern brain …

[HTML][HTML] Stem cell plasticity, acetylation of H3K14, and de novo gene activation rely on KAT7

AJ Kueh, MI Bergamasco, A Quaglieri, B Phipson… - Cell Reports, 2023 - cell.com
In the conventional model of transcriptional activation, transcription factors bind to response
elements and recruit co-factors, including histone acetyltransferases. Contrary to this model …

Canonical and non-canonical reelin signaling

HH Bock, P May - Frontiers in cellular neuroscience, 2016 - frontiersin.org
Reelin is a large secreted glycoprotein that is essential for correct neuronal positioning
during neurodevelopment and is important for synaptic plasticity in the mature brain …

How does Reelin control neuronal migration and layer formation in the developing mammalian neocortex?

K Sekine, K Kubo, K Nakajima - Neuroscience research, 2014 - Elsevier
The mammalian neocortex has a laminar structure that develops in a birth-date-dependent
“inside-out” pattern. Its layered structure is established by neuronal migration accompanied …

Functional implications of miR-19 in the migration of newborn neurons in the adult brain

J Han, HJ Kim, ST Schafer, A Paquola, GD Clemenson… - Neuron, 2016 - cell.com
Altered microRNA profiles have been implicated in human brain disorders. However, the
functional contribution of individual microRNAs to neuronal development and function is …