Major depressive disorder (MDD) is characterized by psychological and physiological
manifestations contributing to the disease severity and outcome. In recent years, several …

Global levels of obesity are reaching epidemic proportions, leading to a dramatic increase in
incidence of secondary diseases and the significant economic burden associated with their …

Background Vascular depression is regarded as a subtype of late-life depression
characterized by a distinct clinical presentation and an association with cerebrovascular …

Despite the lower prevalence of severe mood disorders in the elderly as compared to
younger adults, late-life depression and bipolar disorder (BD) are more strongly associated …

Major depression disorder is a severe mental illness often linked with metabolic disorders.
Adiponectin is an adipocyte-secreted circulatory hormone with antidiabetic and glucose/lipid …

Background Major depressive disorder (MDD) is a complex mental health condition that
results in several obstacles including disabilities, loss of productivity, and economic burdens …

The pathological hallmarks of Alzheimer's disease (AD) include amyloid beta (Aβ)
accumulation, neurofibrillary tangle formation, synaptic dysfunction and neuronal loss. In this …

Receptors of leptin, the prototypical adipokine, are expressed throughout the cortex and
several other areas of the brain. Although typically studied for its role in energy intake and …

Adiponectin, an adipocytokine released by the adipose tissue and has important roles in the
metabolic regulation and inflammatory control, may play an important roles in the …

Adiponectin, leptin and resistin may play a role in the pathophysiology of major depressive
disorder (MDD). However, differences in peripheral levels of these hormones are …