Endocytosis of abiotic nanomaterials and nanobiovectors: Inhibition of membrane trafficking

P Makvandi, M Chen, R Sartorius, A Zarrabi… - Nano Today, 2021 - Elsevier
Humans are exposed to nanoscopical nanobiovectors (eg coronavirus SARS-CoV-2) as
well as abiotic metal/carbon-based nanomaterials that enter cells serendipitously or …

Nanoparticle delivery systems with cell-specific targeting for pulmonary diseases

Z Deng, GT Kalin, D Shi… - American journal of …, 2021 - atsjournals.org
Respiratory disorders are among the most important medical problems threatening human
life. The conventional therapeutics for respiratory disorders are hindered by insufficient drug …

[HTML][HTML] Muscone/RI7217 co-modified upward messenger DTX liposomes enhanced permeability of blood-brain barrier and targeting glioma

S Kang, W Duan, S Zhang, D Chen, J Feng, N Qi - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: The dual-targeted drug delivery system was designed for enhancing permeation
of the blood-brain barrier (BBB) and providing an anti-glioma effect. As transferrin receptor …

Fabrication of egg white protein/phosphatidylcholine-EGCG co-assembled nanoparticles with sustained release in simulated gastrointestinal digestion and their …

M Zhang, X Gao, Y Su, J Li, C Chang, L Gu, Y Yang - Food Hydrocolloids, 2023 - Elsevier
Abstract Epigallocatechin-3-gallate (EGCG) is a kind of polyphenol with various biological
activities but poor stability and bioavailability. The encapsulation of EGCG in a nano-delivery …

Advancements in chitosan-based nanoparticles for pulmonary drug delivery

TM Zacaron, MLS Silva, MP Costa, DM Silva, AC Silva… - Polymers, 2023 - mdpi.com
The evolution of respiratory diseases represents a considerable public health challenge, as
they are among the leading causes of death worldwide. In this sense, in addition to the high …

Nanomedicine for treating muscle dystrophies: opportunities, challenges, and future perspectives

Z Ahmed, R Qaisar - International Journal of Molecular Sciences, 2022 - mdpi.com
Muscular dystrophies are a group of genetic muscular diseases characterized by impaired
muscle regeneration, which leads to pathological inflammation that drives muscle wasting …

Nanomedicine for gene delivery and drug repurposing in the treatment of muscular dystrophies

I Andreana, M Repellin, F Carton, D Kryza, S Briançon… - Pharmaceutics, 2021 - mdpi.com
Muscular Dystrophies (MDs) are a group of rare inherited genetic muscular pathologies
encompassing a variety of clinical phenotypes, gene mutations and mechanisms of disease …

Tumor-targeting glycol chitosan nanoparticles for image-guided surgery of rabbit orthotopic VX2 lung cancer

KC On, J Rho, HY Yoon, H Chang, JY Yhee, JS Yoon… - Pharmaceutics, 2020 - mdpi.com
Theranostic nanoparticles can deliver therapeutic agents as well as diverse imaging agents
to tumors. The enhanced permeation and retention (EPR) effect is regarded as a crucial …

[HTML][HTML] Biomimetic polycaprolactone-chitosan nanofibrous substrate influenced cell cycle and ECM secretion affect cellular uptake of nanoclusters

D Jhala, H Rather, D Kedaria, J Shah, S Singh… - Bioactive materials, 2019 - Elsevier
Biomimetic cell culture substrates are developed as an alternative to the conventional
substrates. They provide necessary biochemical and biophysical cues to the cells from their …

Deep tumor penetration of doxorubicin-loaded glycol chitosan nanoparticles using high-intensity focused ultrasound

Y Choi, H Han, S Jeon, HY Yoon, H Kim, IC Kwon… - Pharmaceutics, 2020 - mdpi.com
The dense extracellular matrix (ECM) in heterogeneous tumor tissues can prevent the deep
tumor penetration of drug-loaded nanoparticles, resulting in a limited therapeutic efficacy in …