Planar polarity describes the coordinated polarisation of cells or structures in the plane of a
tissue. The patterning mechanisms that underlie planar polarity are well characterised in …

Planar cell polarity (PCP) refers to the coordinated alignment of cell polarity across the
tissue plane. Key to the establishment of PCP is asymmetric partitioning of cortical PCP …

Planar cell polarization entails establishment of cellular asymmetries within the tissue plane.
An evolutionarily conserved planar cell polarity (PCP) signaling system employs intra-and …

Background Airway cilia must be physically oriented along the longitudinal tissue axis for
concerted, directional motility that is essential for proper mucociliary clearance. Results We …

Microtubules are core components of the cytoskeleton and serve as tracks for motor protein–
based intracellular transport. Microtubule networks are highly diverse across different cell …

Planar cell polarization represents the ability of cells to orient within the plane of a tissue
orthogonal to the apical basal axis. The proper polarized function of multiciliated cells …

Cell polarity is essential for cells to divide asymmetrically, form spatially restricted
subcellular structures and participate in three-dimensional multicellular organization. PAR …

Coordinated rearrangements of cytoskeletal structures are the principal source of forces that
govern cell and tissue morphogenesis,. However, unlike for actin-based mechanical forces …

Planar cell polarity (PCP) in epithelia, orthogonal to the apical–basal axis, is essential for
numerous developmental events and physiological functions. Drosophila model systems …

Planar cell rearrangements control epithelial tissue morphogenesis and cellular pattern
formation. They lead to the formation of new junctions whose length and stability determine …