One of the most common lipids in the human body is palmitic acid (PA), a saturated fatty acid
with essential functions in brain cells. PA is used by cells as an energy source, besides …

In mammals, sexual hormones such as estrogens play an essential role in maintaining brain
homeostasis and function. Estrogen deficit in the brain induces many undesirable symptoms …

Understanding metabolic heterogeneity is the key to uncovering the underlying mechanisms
of metabolic-related diseases. Current metabolic imaging studies suffer from limitations …

Synthetic selective modulators of the estrogen receptors (SERMs) have shown to protect
neurons and glial cells against toxic insults. Among the most relevant beneficial effects …

Traumatic brain injury (TBI) is characterized by a complex network of signals mediating
inflammatory, proliferative and apoptotic processes during its acute and chronic phases …

Neuroinflammation has been implicated in the pathogenesis of neurodegeneration and is
now accepted as a common molecular feature underpinning neuronal damage and death …

Autophagy is an essential mechanism to maintain cellular homeostasis. Besides its role in
controlling the quality of cytoplasmic components, it participates in nutrient obtaining and …

Traumatic brain injury (TBI) is a serious public health problem. It may result in severe
neurological disabilities and in a variety of cellular metabolic alterations for which available …

Traumatic brain injury (TBI) is a pathology of great social impact, affecting millions of people
worldwide. Despite the scientific advances to improve the management of TBI in recent …

The high concentrations of free fatty acids as a consequence of obesity and being
overweight have become risk factors for the development of different diseases, including …