Behavioural and psychological symptoms of dementia (BPSD) occur in most patients with
dementia. They cause great suffering in patients and caregivers, sometimes more so than …

Neuropsychiatric symptoms (NPS) are very common in Alzheimer's disease (AD),
particularly agitation, apathy, depression, and delusions. Brain networks or circuits …

Introduction Apathy is common in neurocognitive disorders (NCDs) such as Alzheimer's
disease and mild cognitive impairment. Although the definition of apathy is inconsistent in …

Objective: In a recent crossover trial, methylphenidate treatment decreased apathy in
Alzheimer's disease. We further assessed this finding in the Apathy in Dementia …

Background Despite the high prevalence of apathy in Alzheimer's disease (AD), and its
harmful effects, there are currently no therapies proven to treat this symptom. Recently, a …

Apathy is generally defined as a disorder of motivation and is considered one of the most
common neuropsychiatric disturbances in Parkinson's disease (PD). Only few studies …

The objective of this study was to examine the prevalence and clinical correlates of apathy in
a population-based sample of patients with Parkinson's disease (PD) and to assess whether …

Neuropsychiatric symptoms of Alzheimer's disease (NPS-AD) are highly prevalent and lead
to poor medical and functional outcomes. In spite of the burdensome nature of NPS-AD, we …

Apathy is an increasingly recognized concomitant of a broad range of central nervous
system disorders. Nevertheless, its nosology, pathogenesis and therapy remain shrouded in …

Apathy, or a lack of motivation, has been increasingly recognized as a distinct psychiatric
syndrome. Apathy is primarily a dysfunction of the frontal-subcortical circuit and is …