The TRIM/RBCC proteins are defined by the presence of the tripartite motif composed of a
RING domain, one or two B‐box motifs and a coiled‐coil region. These proteins are involved …

Myosins are a large family of actin-based cytoskeletal motors that use energy derived from
ATP hydrolysis to generate movement and force. Myosins of classes II, V and VI have …

Trim32 belongs to the tripartite motif (TRIM) protein family, which is characterized by a
common domain structure composed of a RING-finger, a B-box, and a coiled-coil motif. In …

MicroRNAs (miRNAs) are small non-coding RNA regulators of protein synthesis that are
essential for normal brain development and function. Their profiles are significantly altered …

Myosin‐V is a versatile motor involved in short‐range transport of vesicles in the actin‐rich
cortex of the cell. It binds to several different kinds of vesicles, and the mechanism by which …

In C. elegans, heterochronic genes control the timing of cell fate determination during
development. Two heterochronic genes, let‐7 and lin‐4, encode microRNAs (miRNAs) that …

Eukaryotic cells organize their cytoplasm by moving different organelles and
macromolecular complexes along microtubules and actin filaments. These movements are …

TRIM-NHL proteins are key regulators of developmental transitions, for example promoting
differentiation, while inhibiting cell growth and proliferation, in stem and progenitor cells …

TRIM RING finger proteins have been shown to play an important role in cancerogenesis, in
the pathogenesis of some human hereditary disorders, and in the defense against viral …

TRIM proteins constitute a large, diverse and ancient protein family which play a key role in
processes including cellular differentiation, autophagy, apoptosis, DNA repair, and tumour …