Network pharmacology, a promising approach to reveal the pharmacology mechanism of Chinese medicine formula

L Zhao, H Zhang, N Li, J Chen, H Xu, Y Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Network pharmacology is a new discipline based on
systems biology theory, biological system network analysis, and multi-target drug molecule …

The role of inflammation in cardiovascular disease

MY Henein, S Vancheri, G Longo… - International journal of …, 2022 - mdpi.com
Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

Metabolic syndrome and cardiovascular diseases: Going beyond traditional risk factors

JL Silveira Rossi, SM Barbalho… - Diabetes/metabolism …, 2022 - Wiley Online Library
Metabolic syndrome (MS) is a chronic non‐infective syndrome characterised clinically by a
set of vascular risk factors that include insulin resistance, hypertension, abdominal obesity …

[HTML][HTML] Macrophage membrane functionalized biomimetic nanoparticles for targeted anti-atherosclerosis applications

Y Wang, K Zhang, T Li, A Maruf, X Qin, L Luo… - Theranostics, 2021 - ncbi.nlm.nih.gov
Atherosclerosis (AS), the underlying cause of most cardiovascular events, is one of the most
common causes of human morbidity and mortality worldwide due to the lack of an efficient …

Multifunctional role of S100 protein family in the immune system: an update

P Singh, SA Ali - Cells, 2022 - mdpi.com
S100 is a broad subfamily of low-molecular weight calcium-binding proteins (9–14 kDa) with
structural similarity and functional discrepancy. It is required for inflammation and cellular …

Thrombosis in Coronavirus disease 2019 (COVID-19) through the prism of Virchow's triad

S Ahmed, O Zimba, AY Gasparyan - Clinical Rheumatology, 2020 - Springer
The pathogenesis of Coronavirus disease 2019 (COVID-19) is gradually being
comprehended. A high number of thrombotic episodes are reported, along with the mortality …

Suppression of apoptosis in vascular endothelial cell, the promising way for natural medicines to treat atherosclerosis

H Duan, Q Zhang, J Liu, R Li, D Wang, W Peng… - Pharmacological …, 2021 - Elsevier
Atherosclerosis, a chronic multifactorial disease, is closely related to the development of
cardiovascular diseases and is one of the predominant causes of death worldwide. Normal …

[HTML][HTML] Berberine in cardiovascular and metabolic diseases: from mechanisms to therapeutics

X Feng, A Sureda, S Jafari, Z Memariani, D Tewari… - Theranostics, 2019 - ncbi.nlm.nih.gov
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide,
underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is …

PCSK9 biology and its role in atherothrombosis

C Barale, E Melchionda, A Morotti, I Russo - International journal of …, 2021 - mdpi.com
It is now about 20 years since the first case of a gain-of-function mutation involving the as-yet-
unknown actor in cholesterol homeostasis, proprotein convertase subtilisin/kexin type 9 …

The gut microbial metabolite trimethylamine N-oxide and cardiovascular diseases

J Zhen, Z Zhou, M He, HX Han, EH Lv… - Frontiers in …, 2023 - frontiersin.org
Morbidity and mortality of cardiovascular diseases (CVDs) are exceedingly high worldwide.
Researchers have found that the occurrence and development of CVDs are closely related …