[HTML][HTML] Cytochrome P450: polymorphisms and roles in cancer, diabetes and atherosclerosis
Cytochromes P450s (CYPs) constitute a superfamily of enzymes that catalyze the
metabolism of drugs and other substances. Endogenous substrates of CYPs include …
metabolism of drugs and other substances. Endogenous substrates of CYPs include …
The multifarious link between cytochrome P450s and cancer
AM Alzahrani, P Rajendran - Oxidative Medicine and Cellular …, 2020 - Wiley Online Library
Cancer is a leading cause of death worldwide. Cytochrome P450s (P450s) play an
important role in the metabolism of endogenous as well as exogenous substances …
important role in the metabolism of endogenous as well as exogenous substances …
Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner
Eicosapentaenoic acid (EPA) has garnered attention after the success of the REDUCE‐IT
trial, which contradicted previous conclusions on EPA for cardiovascular disease risk. Here …
trial, which contradicted previous conclusions on EPA for cardiovascular disease risk. Here …
Potential impact of microRNA gene polymorphisms in the pathogenesis of diabetes and atherosclerotic cardiovascular disease
MicroRNAs (miRNAs) are endogenous, small (18–23 nucleotides), non-coding RNA
molecules. They regulate the posttranscriptional expression of their target genes. MiRNAs …
molecules. They regulate the posttranscriptional expression of their target genes. MiRNAs …
Polyunsaturated fatty acids, specialized pro-resolving mediators, and targeting inflammation resolution in the age of precision nutrition
AE Al-Shaer, N Buddenbaum, SR Shaikh - Biochimica et Biophysica Acta …, 2021 - Elsevier
Chronic inflammation contributes toward the pathogenesis of numerous diseases including,
but not limited to, obesity, autoimmunity, cardiovascular diseases, and cancers. The …
but not limited to, obesity, autoimmunity, cardiovascular diseases, and cancers. The …
Glutathione S-Transferase (GSTT1 rs17856199) and Nitric Oxide Synthase (NOS2 rs2297518) Genotype Combination as Potential Oxidative Stress-Related …
AMT Gusti, SY Qusti, SM Bahijri, EA Toraih… - Diabetes, Metabolic …, 2021 - Taylor & Francis
Background Deregulation of the antioxidant enzymes was implicated in pathogenesis and
complications of type 2 diabetes mellitus (T2DM). The data relate the genetic variants of …
complications of type 2 diabetes mellitus (T2DM). The data relate the genetic variants of …
Evaluation of the association of omentin 1 rs2274907 a> t and rs2274908 g> a gene polymorphisms with coronary artery disease in Indian population: a case control …
Coronary artery disease (CAD) is a major cause of death all over the world. CAD is caused
by atherosclerosis which is induced by the interaction of genetic factors and environmental …
by atherosclerosis which is induced by the interaction of genetic factors and environmental …
Genetic determinants of cardiovascular disease: the endothelial nitric oxide synthase 3 (eNOS3), Krüppel-like factor-14 (KLF-14), methylenetetrahydrofolate reductase …
Coronary artery disease (CAD) is an important cause of death worldwide. CAD is caused by
genetic and other factors including hypertension, hyperlipidemia, obesity, stress, unhealthy …
genetic and other factors including hypertension, hyperlipidemia, obesity, stress, unhealthy …
Analysis of the Potential Association of Drug-metabolizing Enzymes CYP2C9∗ 3 and CYP2C19∗ 3 Gene Variations with Type 2 Diabetes: A Case-control Study
Background: Cytochrome P450s (CYPs) are drug-metabolizing enzymes catalyzing the
metabolism of about 75% of drug in clinical use. CYP2C9 represents 20% CYP proteins in …
metabolism of about 75% of drug in clinical use. CYP2C9 represents 20% CYP proteins in …
Clinical Implications of MiR128, Angiotensin I Converting Enzyme and Vascular Endothelial Growth Factor Gene Abnormalities and Their Association with T2D
Type 2 DM (T2D) results from the interaction of the genetic and environmental risk factors.
Vascular endothelial growth factor (VEGF), angiotensin I-converting enzyme (ACE), and …
Vascular endothelial growth factor (VEGF), angiotensin I-converting enzyme (ACE), and …