Cardiovascular diseases (CVDs) are the major causes of mortality in persons with diabetes,
and many factors, including hypertension, contribute to this high prevalence of CVD …

Bell comments on diabetic cardiomyopathy, arguing that its prevalence in type 2 diabetic
patients is higher than was previously believed, and that diabetic cardiomyopathy is due to …

Diabetic cardiomyopathy is characterized by ventricular dysfunction that occurs in diabetic
patients independent of coronary artery disease, hypertension, and any other cardiovascular …

Increased hexosamine biosynthesis pathway (HBP) flux and elevated levels of protein O-
linked-N-acetylglucosamine (O-GlcNAc) decrease calcium influx into isolated …

Hyperglycemia alters cardiac function and often leads to diabetic cardiomyopathy as
cardiomyocyte apoptosis causes a hypertrophied heart to deteriorate to dilation and failure …

Diabetes-induced hyperlipidemia, oxidative stress and protein glycation impair cellular
calcium and sodium homeostasis associated with abnormal membrane-bound enzyme …

When the equilibrium between free-radical production and cellular antioxidant defences is
disturbed in favour of more free radicals, it causes oxidative stress which can promote …

The cardioprotective nature of tangeretin, a polymethoxylated flavone present in citrus fruits,
was investigated by assessing the key markers of heart, lipid profiles, oxidative stress …

Diabetic encephalopathy is characterized by impaired cognitive functions that appear to
underlie neuronal damage triggered by glucose driven oxidative stress. Hyperglycemia …

Hyperglycemia leads to excess production of reactive oxygen species (ROS), lipid
peroxidation and protein glycation that may impair cellular calcium homeostasis and results …