CD8+ lymphocytes are adaptive immunity cells with the particular function to directly kill the
target cell following antigen recognition in the context of MHC class I. In addition, CD8+ T …

Memory CD8+ T cells can be broadly divided into circulating (T CIRCM) and tissue-resident
memory T (T RM) populations. Despite well-defined migratory and transcriptional …

Tissue-resident memory T (T RM) cells serve as a first line of defense in peripheral tissues to
protect the organism against foreign pathogens. However, autoreactive T RM cells are …

SARS-CoV-2 infection for most children results in mild or minimal symptoms, though in rare
cases severe disease can develop, including a multisystem inflammatory syndrome (MIS-C) …

Rheumatoid arthritis (RA) is a highly disabling, systemic autoimmune disease. It presents a
remarkable tendency to recur, which renders it almost impossible for patients to live without …

Resident memory T cells (T-RMs) remain in epithelial barrier tissues after antigen exposure
and the initial effector phase. These T-RMs provide effective antimicrobial and anticancer …

The persistent murine norovirus strain MNVCR6 is a model for human norovirus and enteric
viral persistence. MNVCR6 causes chronic infection by directly infecting intestinal tuft cells …

INTRODUCTION: Viral infections have been associated with the progression of
atherosclerosis and CD8+ T-cells directed against common viruses, such as influenza …

Clonotypic αβ T cell responses to cargoes presented by major histocompatibility complex
(MHC), MR1, or CD1 proteins underpin adaptive immunity. Those responses are mostly …

Tissue-resident lymphocytes provide organ-adapted protection against invading pathogens.
Whereas their biology has been examined in great detail in various infection models, their …