Epigenetic modifications are increasingly recognized to play a role in the etiology and
pathophysiology of schizophrenia and other psychiatric disorders with developmental …

Schizophrenia is a chronic, heterogeneous neurodevelopmental disorder that has complex
symptoms and uncertain etiology. Mounting evidence indicates the involvement of genetics …

Purpose A limit on developing new treatments for a number of central nervous system (CNS)
disorders has been the inadequate understanding of the in vivo pathophysiology underlying …

Histone deacetylases (HDACs) are a large family of epigenetic metalloenzymes that are
involved in gene transcription and regulation, cell proliferation, differentiation, migration, and …

This review is focused on several psychiatric disorders in which cognitive impairment is a
major component of the disease, influencing life quality. There are plenty of data proving that …

Given its chronicity, contribution to disability and morbidity, and prevalence of more than 2%,
the effective treatment, and prevention of bipolar disorder represents an area of significant …

The etiology of autism spectrum disorder (ASD) remains unknown, but gene-environment
interactions, mediated through epigenetic mechanisms, are thought to be a key contributing …

Schizophrenia (SZ) is a neurodevelopmental disorder with cognitive deficits manifesting
during early stages of the disease. Evidence suggests that genetic factors in combination …

Neurodegenerative diseases (NDDs) and neuropsychiatric disorders (NPDs) are two
common causes of death in elderly people, which includes progressive neuronal cell death …

Chromosomal organization, scaling from the 147-base pair (bp) nucleosome to megabase-
ranging domains encompassing multiple transcriptional units, including heritability loci for …