High-density lipoproteins (HDLs) are heterogeneous lipoproteins that modify their
composition and functionality depending on physiological or pathological conditions. The …

Leishmaniasis is a neglected tropical disease caused by parasites of the genus Leishmania.
As approved human vaccines are not available, treatment and prevention rely heavily on …

This study aimed to identify the potential allergenic peptides and critical amino acids derived
from the digestive products of glycated α-lactalbumin. Degranulation assays showed that …

Macrophages play a pivotal role as host cells for Leishmania parasites, displaying a notable
functional adaptability ranging from the proinflammatory, leishmanicidal M1 phenotype to …

The viral entry consists of several sequential events that ensure the attachment of the virus
to the host cell and the introduction of its genetic material for the continuation of the …

The first step of successful infection by any intracellular pathogen relies on its ability to
invade its host cell membrane. However, the detailed structural and molecular …

Leishmania parasites are capable of effectively invading dendritic cells (DCs), a cell
population orchestrating immune responses against several diseases, including …

Leishmaniasis is a group of infectious diseases caused by protozoa of the Leishmania
genus and its immunopathogenesis results from an unbalanced immune response during …

Background Leishmaniasis is mainly prevalent in tropical and subtropical developing
countries, where chronic undernutrition often co-exists. Undernutrition is reported to promote …

It is known that conventional antigen presentation involves phagocytosis of antigens
followed by its internalization in endocytic compartments and presentation of epitopes …