Research progress on antibacterial activities and mechanisms of natural alkaloids: A review

Y Yan, X Li, C Zhang, L Lv, B Gao, M Li - Antibiotics, 2021 - mdpi.com
Alkaloids are nitrogen-containing heterocyclic compounds typically isolated from plants.
They represent one of the most important types of natural products because of their large …

Thiazole-based analogs as potential antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA) and their SAR elucidation

J Guo, Z Xie, W Ruan, Q Tang, D Qiao, W Zhu - European Journal of …, 2023 - Elsevier
In recent years, the overuse of antibiotics has resulted in the emergence of antibiotic
resistance, which is a serious global health problem. Methicillin-resistant Staphylococcus …

Curcumin-loaded scaffolds in bone regeneration

ME Astaneh, F Noori, N Fereydouni - Heliyon, 2024 - cell.com
In recent years, there has been a notable surge in the development of engineered bone
scaffolds intended for the repair of bone defects. While autografts and allografts have …

Natural products against key Mycobacterium tuberculosis enzymatic targets: Emerging opportunities for drug discovery

G Cazzaniga, M Mori, LR Chiarelli, A Gelain… - European journal of …, 2021 - Elsevier
For centuries, natural products (NPs) have served as powerful therapeutics against a variety
of human ailments. Nowadays, they still represent invaluable resources for the treatment of …

A new water-soluble bactericidal agent for the treatment of infections caused by Gram-positive and Gram-negative bacterial strains

A Presentato, E Piacenza, A Scurria, L Albanese… - Antibiotics, 2020 - mdpi.com
Grapefruit and lemon pectin obtained from the respective waste citrus peels via
hydrodynamic cavitation in water only are powerful, broad-scope antimicrobials against …

Recent progress of bacterial FtsZ inhibitors with a focus on peptides

H Han, Z Wang, T Li, D Teng, R Mao, Y Hao… - The FEBS …, 2021 - Wiley Online Library
In recent years, the rise of antibiotic resistance has become a primary health problem. With
the emergence of bacterial resistance, the need to explore and develop novel antibacterial …

Synergistic Oxidative Damage with Gene Therapy Potentiates Targeted Sterilization of Broad‐Spectrum Microorganisms

S Huang, Y Song, X Chen, Q Min… - Advanced Functional …, 2023 - Wiley Online Library
Nanoparticle‐based approaches addressed the barriers to antibiotic resistance faced by
traditional antimicrobial agents. However, nanotherapies against multibacterial infections …

A Comparative Study of the Inhibitory Action of Berberine Derivatives on the Recombinant Protein FtsZ of E. coli

A Di Somma, C Canè, NP Rotondo… - International Journal of …, 2023 - mdpi.com
Medicinal plants belonging to the genus Berberis may be considered an interesting source
of drugs to counteract the problem of antimicrobial multiresistance. The important properties …

Targeting Filamenting temperature-sensitive mutant Z (FtsZ) with bioactive phytoconstituents: An emerging strategy for antibacterial therapy

BS Alotaibi - Plos one, 2023 - journals.plos.org
The rise and widespread occurrence of bacterial resistance has created an evident need for
novel antibacterial drugs. Filamenting temperature-sensitive mutant Z (FtsZ) is a crucial …

iTRAQ-based quantitative proteomic analysis of the antibacterial mechanism of silver nanoparticles against multidrug-resistant Streptococcus suis

B Liu, D Liu, T Chen, X Wang, H Xiang… - Frontiers in …, 2023 - frontiersin.org
Background The increase in antibiotic resistance of bacteria has become a major concern in
clinical treatment. Silver nanoparticles (AgNPs) have significant antibacterial effects against …