[HTML][HTML] The extracellular matrix of mycobacterial biofilms: could we shorten the treatment of mycobacterial infections?

P Chakraborty, A Kumar - Microbial cell, 2019 - ncbi.nlm.nih.gov
A number of non-tuberculous mycobacterium species are opportunistic pathogens and
ubiquitously form biofilms. These infections are often recalcitrant to treatment and require …

[HTML][HTML] Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis

P Chakraborty, S Bajeli, D Kaushal, BD Radotra… - Nature …, 2021 - nature.com
Tuberculosis is a chronic disease that displays several features commonly associated with
biofilm-associated infections: immune system evasion, antibiotic treatment failures, and …

Mycobacterial biofilms as players in human infections: a review

EI Niño-Padilla, C Velazquez, A Garibay-Escobar - Biofouling, 2021 - Taylor & Francis
The role of biofilms in pathogenicity and treatment strategies is often neglected in
mycobacterial infections. In recent years, the emergence of nontuberculous mycobacterial …

Characterization of cellulose-degrading bacteria isolated from soil and the optimization of their culture conditions for cellulase production

AL Mokale Kognou, C Chio, JR Khatiwada… - Applied Biochemistry …, 2022 - Springer
The characterization of bacteria with hydrolytic potential significantly contributes to the
industries. Six cellulose-degrading bacteria were isolated from mixture soil samples …

[HTML][HTML] Cellulase promotes mycobacterial biofilm dispersal in response to a decrease in the bacterial metabolite gamma-aminobutyric acid

J Zhang, Y Liu, J Hu, G Leng, X Liu, Z Cui… - International Journal of …, 2024 - mdpi.com
Biofilm dispersal contributes to bacterial spread and disease transmission. However, its
exact mechanism, especially that in the pathogen Mycobacterium tuberculosis, is unclear. In …

S-Adenosylmethionine (SAM)-Dependent Methyltransferase MftM is Responsible for Methylation of the Redox Cofactor Mycofactocin

M Ellerhorst, SA Barth, AP Graça… - ACS Chemical …, 2022 - ACS Publications
Mycobacteria produce several unusual cofactors that contribute to their metabolic versatility
and capability to survive in different environments. Mycofactocin (MFT) is a redox cofactor …

[HTML][HTML] Mycobacterial adhesion: from hydrophobic to receptor-ligand interactions

A Viljoen, YF Dufrêne, J Nigou - Microorganisms, 2022 - mdpi.com
Adhesion is crucial for the infective lifestyles of bacterial pathogens. Adhesion to non-living
surfaces, other microbial cells, and components of the biofilm extracellular matrix are crucial …

[HTML][HTML] Media component bovine serum albumin facilitates the formation of mycobacterial biofilms in response to reductive stress

PS Mavi, S Singh, A Kumar - BMC microbiology, 2023 - Springer
Abstract Background Mycobacterium tuberculosis (Mtb) forms physiologically relevant
biofilms harboring drug-tolerant bacteria. This observation has brought the study of …

Biofilms and Mycobacterium tuberculosis

MJ Brennan - Infection and immunity, 2017 - Am Soc Microbiol
There is good evidence that Mycobacterium tuberculosis evolved with Homo sapiens and,
like our ancestors, migrated throughout the rest of the world from Africa some 70,000 years …

[HTML][HTML] mbtD and celA1 association with ethambutol resistance in Mycobacterium tuberculosis: A multiomics analysis

Z Wu, Q Tan, C Zhang, Y Zhao, Q Liao, M Yu… - Frontiers in Cellular …, 2022 - frontiersin.org
Ethambutol (EMB) is a first-line antituberculosis drug currently being used clinically to treat
tuberculosis. Mutations in the embCAB operon are responsible for EMB resistance …