Breast cancer (BC) is one of the most prevalent cancers in women. Triple-negative breast
cancer (TNBC) in which the three major receptors ie estrogen receptor (ER), progesterone …

Many factors including genetic, environmental, and acquired are involved in breast cancer
development across various societies. Among all of these factors in families with a history of …

Germline mutations in BRCA1 and BRCA2 confer high risks of breast and ovarian cancer,
but the average magnitude of these risks is uncertain and may depend on the context …

Germline mutations in the BRCA1 or BRCA2 tumour-suppressor genes are strong predictors
of breast and/or ovarian cancer development. The contribution of these mutations to breast …

PURPOSE: To provide guidance for clinicians about the diagnosis, staging and treatment of
breast cancer occurring during an otherwise uncomplicated pregnancy. METHODS: An …

Although well studied in families at high-risk, the roles of mutations in the BRCA1 and
BRCA2 genes are poorly understood in breast cancers in the general population …

Breast cancer (BC) is the most common cancer of women all over the world. BRCA1 and
BRCA2 gene mutations comprise the most important genetic susceptibility of BC. Except for …

ContextInformation on the prevalence of pathogenic BRCA1 mutation carriers in
racial/ethnic minority populations is limited. ObjectiveTo estimate BRCA1 carrier prevalence …

Basal-like breast cancer (BBC) is a subtype of breast cancer with poor prognosis,,. Inherited
mutations of BRCA1, a cancer susceptibility gene involved in double-strand DNA break …

Detection of mutations in hereditary breast and ovarian cancer-related BRCA1 and BRCA2
genes is an effective method of cancer prevention and early detection. Different ethnic and …