The epidemiology of venous thromboembolism

RH White - Circulation, 2003 - Am Heart Assoc
Venous thromboembolism (VTE) occurs for the first time in≈ 100 persons per 100,000 each
year in the United States, and rises exponentially from< 5 cases per 100,000 persons< 15 …

Chronobiology, drug delivery, and chronotherapeutics

MH Smolensky, NA Peppas - Advanced drug delivery reviews, 2007 - Elsevier
Biological processes and functions are organized in space, as a physical anatomy, and time,
as a biological time structure. The latter is expressed by short-, intermediate-, and long …

[HTML][HTML] Winter cardiovascular diseases phenomenon

A Fares - North American journal of medical sciences, 2013 - ncbi.nlm.nih.gov
This paper review seasonal patterns across twelve cardiovascular diseases: Deep venous
thrombosis, pulmonary embolism, aortic dissection and rupture, stroke, intracerebral …

Circadian variation in stroke onset: identical temporal pattern in ischemic and hemorrhagic events

R Manfredini, B Boari, MH Smolensky… - Chronobiology …, 2005 - Taylor & Francis
Stroke is the culmination of a heterogeneous group of cerebrovascular diseases that is
manifested as ischemia or hemorrhage of one or more blood vessels of the brain. The …

Circadian rhythms and clinical medicine with applications to hypertension

MH Smolensky, E Haus - American journal of hypertension, 2001 - academic.oup.com
Abstract Circadian (24-h) rhythms are important to the practice of medicine. The phasing and
amplitude of key physiologic and biochemical circadian rhythms contribute to predictable-in …

Dynamics of case-fatalilty rates of recurrent thromboembolism and major bleeding in patients treated for venous thromboembolism

R Lecumberri, A Alfonso, D Jiménez… - Thrombosis and …, 2013 - thieme-connect.com
In patients with venous thromboembolism (VTE), assessment of the risk of fatal recurrent
VTE and fatal bleeding during anticoagulation may help to guide intensity and duration of …

Patient demographic and clinical features and circadian variation in onset of ischemic stroke

I Casetta, E Granieri, E Fallica, O la Cecilia… - Archives of …, 2002 - jamanetwork.com
Background Studies have reported circadian variation in the onset of ischemic stroke, which
may carry important pathophysiological implications. However, there is no detailed …

[图书][B] Blood pressure monitoring in cardiovascular medicine and therapeutics

WB White - 2007 - Springer
Therapeutics is devoted to the topic of circadian variation in cardiovascular disease, with a
special emphasis on blood pressure and the clinical evaluation and treatment of …

Lower ambient temperature was associated with an increased risk of hospitalization for stroke and acute myocardial infarction in young women

CL Chang, M Shipley, M Marmot, N Poulter - Journal of clinical …, 2004 - Elsevier
OBJECTIVE: Results of investigations into the impact of seasonal variation on the incidence
of cardiovascular diseases (CVD) have been inconsistent. Using the WHO Collaborative …

Diurnal and twenty-four hour patterning of human diseases: cardiac, vascular, and respiratory diseases, conditions, and syndromes

MH Smolensky, F Portaluppi, R Manfredini… - Sleep Medicine …, 2015 - Elsevier
Various medical conditions, disorders, and syndromes exhibit predictable-in-time diurnal
and 24 h patterning in the signs, symptoms, and grave nonfatal and fatal events, eg …