Clinical remission attainment, definitions, and correlates among patients with severe asthma treated with biologics: a systematic review and meta-analysis

A Shackleford, LG Heaney, C Redmond… - The Lancet …, 2025 - thelancet.com
Background Clinical remission has emerged as an important treatment goal in severe
asthma; however, studies have reported variable attainment due to differences in study …

An Overview of Adherence-What it is and Why it is Important

ER Conroy, TM Banzon, T Simoneau… - The Journal of Allergy …, 2024 - Elsevier
Asthma, allergic rhinitis, and food allergy are common allergic diseases, yet adherence to
many management options remains poor, leading to worse health outcomes and financial …

Comparative effectiveness of sotatercept and approved add-on pulmonary arterial hypertension therapies: a systematic review and network meta-analysis

T Pitre, K Desai, J Mah, D Zeraatkar… - Annals of the American …, 2024 - atsjournals.org
Rationale: There are no direct comparisons of sotatercept to add-on therapies approved for
PAH. Objective: This study aimed to compare the efficacy and safety of add-on sotatercept …

Baseline characteristics of patients enrolled in clinical trials of biologics for severe asthma as potential predictors of outcomes

F Menzella - Journal of Clinical Medicine, 2023 - mdpi.com
(1) Background: Over the past 20 years, monoclonal antibodies have been developed for
the treatment of severe asthma, with numerous randomised controlled trials (RCTs) …

Effects of tezepelumab on quality of life of patients with moderate-to-severe, uncontrolled asthma: systematic review and meta-analysis

GCL Chagas, D Xavier, L Gomes, J Ferri-Guerra… - Current Allergy and …, 2023 - Springer
Abstract Purpose of Review To assess the effects of tezepelumab on quality of life (QoL) in
patients with moderate-to-severe, uncontrolled asthma. Recent Findings Tezepelumab …

A media advocacy toolkit for the allergist-immunologist

AE Conway, E Gupta, M Verdi, WE Berger… - The Journal of Allergy …, 2024 - Elsevier
For clinicians involved in improving healthcare for patients with allergic and immunologic
conditions, advocacy on a broader level through public outreach is key to advancing value …

Type 2 severe asthma: pathophysiology and treatment with biologics

C Pelaia, J Melhorn, TS Hinks, S Couillard… - Expert Review of …, 2024 - Taylor & Francis
Introduction The hallmark of most patients with severe asthma is type 2 inflammation, driven
by innate and adaptive immune responses leading to either allergic or non-allergic …

Biologic agents licensed for severe asthma: a systematic review and meta-analysis of randomised controlled trials

C Kyriakopoulos, A Gogali… - European …, 2024 - Eur Respiratory Soc
Background: Six biologic agents are now approved for patients with severe asthma. This
meta-analysis aimed to assess the efficacy and safety of licensed biologic agents in patients …

[HTML][HTML] Real-World Efficacy of Biological Therapies in Severe Asthma: A Focus on Small Airways

J Ora, P De Marco, E Motta, R Laitano… - Journal of Clinical …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Severe asthma is a challenging condition that often resists traditional
treatments and requires high-dose inhaled corticosteroids and other controllers to manage …

Biologic Therapies for Chronic Obstructive Pulmonary Disease: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

T Pitre, D Lupas, J Mah, M Stanbrook… - COPD: Journal of …, 2025 - Taylor & Francis
Background Despite limited breakthroughs in COPD pharmacotherapy, recent trials have
shown promising results for biologics in COPD patients. However, robust evidence synthesis …