Despite the promising medicinal properties, berberine (BBR), due to its relatively poor
solubility in plasma, low bio-stability and limited bioavailability is not used broadly in clinical …

Phytocompounds are a well-established source of drug discovery due to their unique
chemical and functional diversities. In the area of cancer therapeutics, several …

Understanding the dynamic changes of plant biomolecules is vital for exploring their
mechanisms in the environment. Molecular dynamics (MD) simulation has been widely used …

Tire wear particles are a notable source of tire microplastics (TMPs) in the environment.
However, only a few reports have focused on the aquatic toxicity effects of composite TMPs …

This work aims to investigate experimentally the co-valorisation of olive mill wastewater
(OMW) and olive pomace (OP), using two ratios: OMW: OP 50: 50 and 30: 70, into …

Topoisomerase inhibitors are extensively used in cancer chemotherapy. In the process of
identifying novel anticancer compounds, biological evaluations are crucial and include …

Metabolic reprogramming in cancer is considered to be one of the most important hallmarks
to drive proliferation, angiogenesis, and invasion. AMP-activated protein kinase activation is …

Due to the significantly negative impact of the coronavirus (CoV) disease (COVID-19)
pandemic on the health of the community and the economy, it remains urgent and necessary …

In silico studies were performed using 5-fluorouracil (5-FU) to explore the efficacy of
template docking and facilitate designing of drug nanocarrier systems. The binding of …

Cancer remains the most devastating disease that threatens public health with increasing
incidence year by year worldwide. The anti-cancer property of naturally derived compounds …