Adult brain aging investigated using BMC-mcDESPOT–based myelin water fraction imaging

M Bouhrara, AC Rejimon, LE Cortina, N Khattar… - Neurobiology of …, 2020 - Elsevier
The relationship between regional brain myelination and aging has been the subject of
intense study, with magnetic resonance imaging perhaps the most effective modality for …

[HTML][HTML] In vivo myelin water quantification using diffusion–relaxation correlation MRI: A comparison of 1D and 2D methods

S Endt, M Engel, E Naldi, R Assereto… - Applied Magnetic …, 2023 - Springer
Abstract Multidimensional Magnetic Resonance Imaging (MRI) is a versatile tool for
microstructure mapping. We use a diffusion weighted inversion recovery spin echo (DW-IR …

Myelin heterogeneity for assessing normal appearing white matter myelin damage in multiple sclerosis

P Johnson, IM Vavasour, BJ Stojkova… - Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose Conventional MRI measures of multiple sclerosis (MS)
disease severity, such as lesion volume and brain atrophy, do not provide information about …

Investigating how demyelination is reflected using advanced magnetic resonance imaging in Susac syndrome and multiple sclerosis

P Johnson - 2021 - open.library.ubc.ca
Conventional magnetic resonance imaging (MRI) is a useful qualitative clinical tool for
diagnosing and monitoring neurodegenerative diseases. However, it is not capable of …

Investigating cognitive impairment in multiple sclerosis using myelin water imaging

SL Abel - 2020 - open.library.ubc.ca
Cognitive impairment is a common symptom in multiple sclerosis (MS) that presents in up to
70% of patients. Cognitive symptoms in MS typically manifest as deficits in attention, memory …

[引用][C] Beyond the Mean: Myelin Heterogeneity Index as a Sensitive Metric for Assessing Myelin Damage in Multiple Sclerosis

P Johnson, IM Vavasour, S Abel, LE Lee, S Ristow… - archive.ismrm.org
Myelin water imaging is a quantitative MRI technique that has been used to investigate
myelin content in multiple sclerosis (MS). Three metrics derived from myelin water imaging …