Preparation and use of decellularized extracellular matrix for tissue engineering
The multidisciplinary fields of tissue engineering and regenerative medicine have the
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …
Biomaterials based strategies for skeletal muscle tissue engineering: existing technologies and future trends
Skeletal muscles have a robust capacity to regenerate, but under compromised conditions,
such as severe trauma, the loss of muscle functionality is inevitable. Research carried out in …
such as severe trauma, the loss of muscle functionality is inevitable. Research carried out in …
Extracellular matrix as an inductive scaffold for functional tissue reconstruction
BN Brown, SF Badylak - Translational Research, 2014 - Elsevier
The extracellular matrix (ECM) is a meshwork of both structural and functional proteins
assembled in unique tissue-specific architectures. The ECM both provides the mechanical …
assembled in unique tissue-specific architectures. The ECM both provides the mechanical …
Macrophage phenotype as a predictor of constructive remodeling following the implantation of biologically derived surgical mesh materials
Macrophages have been classified as having plastic phenotypes which exist along a
spectrum between M1 (classically activated; pro-inflammatory) and M2 (alternatively …
spectrum between M1 (classically activated; pro-inflammatory) and M2 (alternatively …
Injectable remote magnetic nanofiber/hydrogel multiscale scaffold for functional anisotropic skeletal muscle regeneration
Developing an injectable anisotropic scaffold with precisely topographic cues to induce 3D
cellular organization plays a critical role in volumetric muscle loss (VML) repair in vivo …
cellular organization plays a critical role in volumetric muscle loss (VML) repair in vivo …
Extracellular matrix scaffolds for cartilage and bone regeneration
KEM Benders, PR Van Weeren, SF Badylak… - Trends in …, 2013 - cell.com
Regenerative medicine approaches based on decellularized extracellular matrix (ECM)
scaffolds and tissues are rapidly expanding. The rationale for using ECM as a natural …
scaffolds and tissues are rapidly expanding. The rationale for using ECM as a natural …
Consequences of ineffective decellularization of biologic scaffolds on the host response
Biologic scaffold materials composed of extracellular matrix (ECM) are routinely used for a
variety of clinical applications. Despite known variations in tissue remodeling outcomes …
variety of clinical applications. Despite known variations in tissue remodeling outcomes …
A hydrogel derived from decellularized dermal extracellular matrix
MT Wolf, KA Daly, EP Brennan-Pierce, SA Johnson… - Biomaterials, 2012 - Elsevier
The ECM of mammalian tissues has been used as a scaffold to facilitate the repair and
reconstruction of numerous tissues. Such scaffolds are prepared in many forms including …
reconstruction of numerous tissues. Such scaffolds are prepared in many forms including …
An acellular biologic scaffold promotes skeletal muscle formation in mice and humans with volumetric muscle loss
Biologic scaffolds composed of naturally occurring extracellular matrix (ECM) can provide a
microenvironmental niche that alters the default healing response toward a constructive and …
microenvironmental niche that alters the default healing response toward a constructive and …
Decellularized tissue and cell-derived extracellular matrices as scaffolds for orthopaedic tissue engineering
CW Cheng, LD Solorio, E Alsberg - Biotechnology advances, 2014 - Elsevier
The reconstruction of musculoskeletal defects is a constant challenge for orthopaedic
surgeons. Musculoskeletal injuries such as fractures, chondral lesions, infections and tumor …
surgeons. Musculoskeletal injuries such as fractures, chondral lesions, infections and tumor …