Hepaciviruses and pegiviruses constitute two closely related sister genera of the family
Flaviviridae. In the past five years, the known phylogenetic diversity of the hepacivirus …

Since one of us co-authored a review on NS5A a decade ago, the hepatitis C virus (HCV)
field has changed dramatically, primarily due to the advent of the JFH-1 cell culture …

The eukaryotic linear motif (ELM http://elm. eu. org) resource is a hub for collecting,
classifying and curating information about short linear motifs (SLiMs). For> 10 years, this …

Proposals are described for the assignment of recently reported viruses, infecting rodents,
bats and other mammalian species, to new species within the Hepacivirus and Pegivirus …

Hepatitis viruses are major threats to human health. During the last decade, highly diverse
viruses related to human hepatitis viruses were found in animals other than primates …

Recent advances in sequencing technologies have greatly enhanced our abilities to identify
novel microbial sequences. Thus, our understanding of the global virome and the virome of …

Nonprimate hepacivirus (NPHV) is the closest known relative of hepatitis C virus (HCV) and
its study could enrich our understanding of HCV evolution, immunity, and pathogenesis …

Background Next-generation sequencing (NGS) allows ultra-deep sequencing of nucleic
acids. The use of sequence-independent amplification of viral nucleic acids without …

To investigate the transmission of novel infectious agents by blood transfusion, we studied
changes in the virome composition of blood transfusion recipients pre-and posttransfusion …

Hepatitis C virus is considered a major public health problem, infecting 2%–3% of the
human population. Hepatitis C virus infection causes acute and chronic liver disease …