Structural insights into type III secretion systems of the bacterial flagellum and injectisome

LJ Worrall, DD Majewski… - Annual Review of …, 2023 - annualreviews.org
Two of the most fascinating bacterial nanomachines—the broadly disseminated rotary
flagellum at the heart of cellular motility and the eukaryotic cell–puncturing injectisome …

Structural basis of torque generation in the bi-directional bacterial flagellar motor

H Hu, M Santiveri, N Wadhwa, HC Berg… - Trends in biochemical …, 2022 - cell.com
The flagellar stator unit is an oligomeric complex of two membrane proteins (MotA 5 B 2) that
powers bi-directional rotation of the bacterial flagellum. Harnessing the ion motive force …

Structural basis of assembly and torque transmission of the bacterial flagellar motor

J Tan, X Zhang, X Wang, C Xu, S Chang, H Wu… - Cell, 2021 - cell.com
The bacterial flagellar motor is a supramolecular protein machine that drives rotation of the
flagellum for motility, which is essential for bacterial survival in different environments and a …

Bacterial flagella hijack type IV pili proteins to control motility

X Liu, S Tachiyama, X Zhou… - Proceedings of the …, 2024 - National Acad Sciences
Bacterial flagella and type IV pili (TFP) are surface appendages that enable motility and
mechanosensing through distinct mechanisms. These structures were previously thought to …

Ion selectivity and rotor coupling of the Vibrio flagellar sodium-driven stator unit

H Hu, PF Popp, M Santiveri, A Roa-Eguiara… - Nature …, 2023 - nature.com
Bacteria swim using a flagellar motor that is powered by stator units. Vibrio spp. are highly
motile bacteria responsible for various human diseases, the polar flagella of which are …

Structural basis of directional switching by the bacterial flagellum

S Johnson, JC Deme, EJ Furlong, JJE Caesar… - Nature …, 2024 - nature.com
The bacterial flagellum is a macromolecular protein complex that harvests energy from uni-
directional ion flow across the inner membrane to power bacterial swimming via rotation of …

Structural basis of the bacterial flagellar motor rotational switching

J Tan, L Zhang, X Zhou, S Han, Y Zhou, Y Zhu - Cell Research, 2024 - nature.com
The bacterial flagellar motor is a huge bidirectional rotary nanomachine that drives rotation
of the flagellum for bacterial motility. The cytoplasmic C ring of the flagellar motor functions …

The bank of swimming organisms at the micron scale (BOSO-Micro)

MF Velho Rodrigues, M Lisicki, E Lauga - Plos one, 2021 - journals.plos.org
Unicellular microscopic organisms living in aqueous environments outnumber all other
creatures on Earth. A large proportion of them are able to self-propel in fluids with a vast …

A multi-state dynamic process confers mechano-adaptation to a biological nanomachine

N Wadhwa, A Sassi, HC Berg, Y Tu - Nature Communications, 2022 - nature.com
Adaptation is a defining feature of living systems. The bacterial flagellar motor adapts to
changes in the external mechanical load by adding or removing torque-generating (stator) …

FliL and its paralog MotF have distinct roles in the stator activity of the Sinorhizobium meliloti flagellar motor

RC Sobe, C Gilbert, L Vo, G Alexandre… - Molecular …, 2022 - Wiley Online Library
The bacterial flagellum is a complex macromolecular machine that drives bacteria through
diverse fluid environments. Although many components of the flagellar motor are conserved …