Pushing the envelope: LPS modifications and their consequences

BW Simpson, MS Trent - Nature Reviews Microbiology, 2019 - nature.com
The defining feature of the Gram-negative cell envelope is the presence of two cellular
membranes, with the specialized glycolipid lipopolysaccharide (LPS) exclusively found on …

Assembly and maintenance of lipids at the bacterial outer membrane

E Lundstedt, D Kahne, N Ruiz - Chemical reviews, 2020 - ACS Publications
The outer membrane of Gram-negative bacteria is essential for their survival in harsh
environments and provides intrinsic resistance to many antibiotics. This membrane is …

Structural basis of lipopolysaccharide extraction by the LptB2FGC complex

Y Li, BJ Orlando, M Liao - Nature, 2019 - nature.com
In Gram-negative bacteria, lipopolysaccharide is essential for outer membrane formation
and antibiotic resistance. The seven lipopolysaccharide transport (Lpt) proteins A–G move …

Structural basis of unidirectional export of lipopolysaccharide to the cell surface

TW Owens, RJ Taylor, KS Pahil, BR Bertani, N Ruiz… - Nature, 2019 - nature.com
Gram-negative bacteria are surrounded by an inner cytoplasmic membrane and by an outer
membrane, which serves as a protective barrier to limit entry of many antibiotics. The …

Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism

X Tang, S Chang, Q Luo, Z Zhang, W Qiao, C Xu… - Nature …, 2019 - nature.com
Lipopolysaccharides (LPS) of Gram-negative bacteria are critical for the defence against
cytotoxic substances and must be transported from the inner membrane (IM) to the outer …

ABC transporters in bacterial nanomachineries

FL Bilsing, MT Anlauf, E Hachani, S Khosa… - International Journal of …, 2023 - mdpi.com
Members of the superfamily of ABC transporters are found in all domains of life. Most of
these primary active transporters act as isolated entities and export or import their substrates …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2017–2018

DJ Harvey - Mass Spectrometry Reviews, 2023 - Wiley Online Library
This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry …

Lipopolysaccharide biosynthesis and transport to the outer membrane of Gram-negative bacteria

P Sperandeo, AM Martorana, A Polissi - Bacterial cell walls and …, 2019 - Springer
Gram-negative bacteria have an outer membrane that is positioned at the frontline of the
cell's interaction with the environment and that serves as a barrier against noxious …

The transmembrane α‐helix of LptC participates in LPS extraction by the LptB2FGC transporter

A Wilson, N Ruiz - Molecular Microbiology, 2022 - Wiley Online Library
Lipopolysaccharide (LPS) is an essential component of the outer membrane of most Gram‐
negative bacteria that provides resistance to various toxic compounds and antibiotics. Newly …

Integration of transcriptomic and proteomic approaches unveils the molecular mechanism of membrane disintegration in Escherichia coli O157: H7 with ultrasonic …

Q He, Y Liu, D Liu, M Guo - Science of The Total Environment, 2021 - Elsevier
Ultrasonic disinfection in wastewater treatment has been studied for years at the phenotypic
level, while the understanding of the molecular inactivation mechanism is still not clear …