Cyclodextrin-based nanosponges: Overview and opportunities

G Utzeri, PMC Matias, D Murtinho… - Frontiers in …, 2022 - frontiersin.org
Nanosponges are solid cross-linked polymeric nano-sized porous structures. This broad
concept involves, among others, metal organic frameworks and hydrogels. The focus of this …

Cyclodextrin–phytochemical inclusion complexes: Promising food materials with targeted nutrition and functionality

Y Hu, C Qiu, Y Qin, X Xu, L Fan, J Wang… - Trends in Food Science & …, 2021 - Elsevier
Background Natural phytochemicals suffer from poor aqueous solubility and storage stability
as well as demonstrate limited bioaccessibility; thus, their effectiveness as food ingredients …

Synthesis of a non-hazardous/smart anti-corrosion nano-carrier based on beta-cyclodextrin-zinc acetylacetonate inclusion complex decorated graphene oxide (β-CD …

A Dehghani, G Bahlakeh, B Ramezanzadeh - Journal of Hazardous …, 2020 - Elsevier
Recently, the high research considerations have been devoted to designing smart coatings
with self-healing propensity along with improved anti-corrosion properties, durability, and …

Hot-melt extrusion as an effective technique for obtaining an amorphous system of curcumin and piperine with improved properties essential for their better biological …

K Wdowiak, R Pietrzak, E Tykarska, J Cielecka-Piontek - Molecules, 2023 - mdpi.com
Poor bioavailability hampers the use of curcumin and piperine as biologically active agents.
It can be improved by enhancing the solubility as well as by using bioenhancers to inhibit …

Amorphous System of Hesperetin and Piperine—Improvement of Apparent Solubility, Permeability, and Biological Activities

K Wdowiak, A Miklaszewski, R Pietrzak… - International Journal of …, 2023 - mdpi.com
The low bioaccessibility of hesperetin and piperine hampers their application as therapeutic
agents. Piperine has the ability to improve the bioavailability of many compounds when co …

Enhancing efficacy and safety of azelaic acid via encapsulation in cyclodextrin nanosponges: Development, characterization and evaluation

A Kumar, R Rao - Polymer bulletin, 2021 - Springer
Azelaic acid (AA), a promising agent for acne and hyperpigmentation disorders, is
associated with side effects viz. rashes, skin irritation, dryness, burning and stinging. Its poor …

β-Cyclodextrin nanosponges inclusion compounds associated with silver nanoparticles to increase the antimicrobial activity of quercetin

S Salazar Sandoval, T Bruna, F Maldonado-Bravo… - Materials, 2023 - mdpi.com
This work aimed to synthesize and characterize a nanocarrier that consisted of a ternary
system, namely β-cyclodextrin-based nanosponge (NS) inclusion compounds (ICs) …

Evaluation of solubility, photostability and antioxidant activity of ellagic acid cyclodextrin nanosponges fabricated by melt method and microwave-assisted synthesis

K Sharma, V Kadian, A Kumar, S Mahant… - Journal of Food Science …, 2022 - Springer
Ellagic acid (EA) is a polyphenolic bioactive with a wide range of pharmacological activities.
Regrettably, it possesses poor solubility, stability and permeability (in the gastrointestinal …

Cyclodextrin nanosponges inclusion compounds associated with gold nanoparticles for potential application in the photothermal release of melphalan and cytoxan

S Salazar, N Yutronic, MJ Kogan, P Jara - International Journal of …, 2021 - mdpi.com
This article describes the synthesis and characterization of β-cyclodextrin-based nano-
sponges (NS) inclusion compounds (IC) with the anti-tumor drugs melphalan (MPH) and …

β-cyclodextrin-based nanosponges inclusion compounds associated with gold nanorods for potential NIR-II drug delivery

S Salazar Sandoval, E Cortés-Adasme… - Pharmaceutics, 2022 - mdpi.com
This article describes the synthesis and characterization of two nanocarriers consisting of β-
cyclodextrin-based nanosponges (NSs) inclusion compounds (ICs) and gold nanorods …