[HTML][HTML] Progress in the studies on the molecular mechanisms associated with multidrug resistance in cancers

L Zhang, B Ye, Z Chen, ZS Chen - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Chemotherapy is one of the important methods to treat cancer, and the emergence of
multidrug resistance (MDR) is one major cause for the failure of cancer chemotherapy …

Ionophores: potential use as anticancer drugs and chemosensitizers

V Kaushik, JS Yakisich, A Kumar, N Azad, AKV Iyer - Cancers, 2018 - mdpi.com
Ion homeostasis is extremely important for the survival of both normal as well as neoplastic
cells. The altered ion homeostasis found in cancer cells prompted the investigation of …

Environmentally relevant concentration of sulfamethoxazole-induced oxidative stress-cascaded damages in the intestine of grass carp and the therapeutic application …

Y Wang, H Zhao, Y Liu, J Li, X Nie, P Huang… - Environmental …, 2021 - Elsevier
Due to the unreasonable use and discharge of the aquaculture industry, over standard of the
antibiotics has been frequent in different types of water environments, causing adverse …

Roles of reactive oxygen species in biological behaviors of prostate cancer

C Han, Z Wang, Y Xu, S Chen, Y Han… - BioMed research …, 2020 - Wiley Online Library
Prostate cancer (PCa), known as a heterogenous disease, has a high incidence and
mortality rate around the world and seriously threatens public health. As an inevitable by …

A mini-review of reactive oxygen species in urological cancer: correlation with NADPH oxidases, angiogenesis, and apoptosis

Y Miyata, T Matsuo, Y Sagara, K Ohba… - International journal of …, 2017 - mdpi.com
Oxidative stress refers to elevated reactive oxygen species (ROS) levels, and NADPH
oxidases (NOXs), which are one of the most important sources of ROS. Oxidative stress …

Ultrastructural changes in cardiac and skeletal myoblasts following in vitro exposure to monensin, salinomycin, and lasalocid

D Henn, AV Lensink, CJ Botha - Plos one, 2024 - journals.plos.org
Carboxylic ionophores are polyether antibiotics used in production animals as feed
additives, with a wide range of benefits. However, ionophore toxicosis often occurs as a …

[PDF][PDF] Docosahexaenoic acid reverses epithelial-mesenchymal transition and drug resistance by impairing the PI3K/AKT/Nrf2/GPX4 signalling pathway in docetaxel …

ZC Shao, BH Zhu, AF Huang, MQ Su, LJ An… - Folia …, 2022 - foliabiologica.lf1.cuni.cz
Drug resistance is a serious problem in cancer therapy. Growing evidence has shown that
docosahexaenoic acid has anti-inflammatory and chemopreventive abilities. Studies have …

m6A RNA Methylation Regulators Impact Prognosis and Tumor Microenvironment in Renal Papillary Cell Carcinoma

L Chen, B Hu, X Song, L Wang, M Ju, Z Li… - Frontiers in …, 2021 - frontiersin.org
Accumulating evidence has proven that N6-methyladenosine (m6A) RNA methylation plays
an essential role in tumorigenesis. However, the significance of m6A RNA methylation …

Ginkgo biloba exocarp extracts induces autophagy in Lewis lung cancer cells involving AMPK/mTOR/p70S6k signaling pathway

C Cao, D Han, Y Su, Y Ge, H Chen, A Xu - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Objectives Ginkgo biloba L. is called a living fossil plant, and could be used for the treatment
of cancer thousands of years ago in China. The extracts prepared from the Ginkgo biloba …

[HTML][HTML] Identification of hub genes and small molecule drugs associated with acquired resistance to gefitinib in non-small cell lung cancer

G Li, Y Ma, M Yu, X Li, X Chen, Y Gao, P Cheng… - Journal of …, 2021 - ncbi.nlm.nih.gov
Targeting EGFR, epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs),
brings lights to the treatment of non-small cell lung cancer (NSCLC). Although T790M …