Oral administration is the most common route of drug delivery. The absorption of a drug from
the gut into the bloodstream involves disintegration of the solid dosage form, dissolution of …

Although it is well known that water is essential for human homeostasis and survival, only
recently have we begun to understand its role in the maintenance of brain function. Herein …

Background: Bioelectrical impedance analysis has evolved over the years to include the use
of multiple frequencies and impedance measurements to improve the accuracy and …

Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a
trinucleotide repeat expansion in the huntingtin (HTT) gene, which is expressed ubiquitously …

Deuterium metabolic spectroscopy (DMS) and imaging (DMI) have recently been described
as simple and robust MR-based methods to map metabolism with high temporal and/or …

Purpose Although low water intake has been associated with adverse health outcomes,
available literature indicated that the majority of children do not meet the water intake …

Biomarkers of hydration change in response to acute dehydration; however, their
responsiveness to changes in fluid intake volume, without exercise or heat exposure, has …

Gluconeogenesis is a complex metabolic process that involves multiple enzymatic steps
regulated by myriad factors, including substrate concentrations, the redox state, activation …

Optimal hydration is required for all physiologic functions and cognition. Children, especially
younger ones, are particularly susceptible to dehydration, given their physiological …

The present study evaluated, using a well-controlled dehydration protocol, the effects of 24 h
fluid deprivation (FD) on selected mood and physiological parameters. In the present cross …