Apoptosis, a form of programmed cell death, is essential for growth and tissue homeostasis.
Apoptotic bodies (ApoBDs) are a form of extracellular vesicles (EVs) released by dying cells …

The ability of animals to regenerate missing parts is a dramatic and poorly understood
aspect of biology. The sources of new cells for these regenerative phenomena have been …

Understanding the molecular mechanisms that promote successful tissue regeneration is
critical for continued advancements in regenerative medicine. Vertebrate amphibian …

Despite their overwhelming complexity, living cells display a high degree of internal
mechanical and functional organization which can largely be attributed to the intracellular …

Most organisms experience changes in regenerative abilities through their lifespan. During
aging, numerous tissues exhibit a progressive decline in homeostasis and regeneration that …

Apoptotic death of osteocytes was recognized over 15years ago, but its significance for bone
homeostasis has remained elusive. A new paradigm has emerged that invokes osteocyte …

Genes dedicated to killing cells must have evolved because of their positive effects on
organismal survival. Positive functions of apoptotic genes have been well established in a …

Salamanders exhibit an extraordinary ability among vertebrates to regenerate complex body
parts. However, scarce genomic resources have limited our understanding of regeneration …

Wnt/β‐catenin signalling is known to play many roles in metazoan development and tissue
homeostasis. Misregulation of the pathway has also been linked to many human diseases …

Deafness caused by the terminal loss of inner ear hair cells is one of the most common
sensory diseases. However, nonmammalian animals (eg, birds, amphibians, and fish) …