Introduction Fatigue, cognitive impairment, depression, and pain are highly prevalent
symptoms in multiple sclerosis (MS). These often co-occur and may be explained by a …

Background Multiple sclerosis (MS) is a disabling disease of the central nervous system.
People living with MS often have co-existing sleep disorders and cognitive dysfunction. The …

Background: Characterization of cognitive impairment (CI) in multiple sclerosis into distinct
phenotypes holds promise for individualized treatments and biomarker exploration …

Background Available criteria for cognitive phenotypes in multiple sclerosis (MS) do not
consider the severity of impairment. Objectives To identify cognitive phenotypes with varying …

As meaningful measure of cognitive impairment (CI), cognitive phenotypes provide an
avenue for symptom management and individualized rehabilitation. Since CI is highly …

Multiple sclerosis (MS) is a devastating immune-mediated disorder of the central nervous
system resulting in progressive disability accumulation. As there is no cure available yet for …

Background People with multiple sclerosis (MS) commonly experience cognitive impairment
associated with the disease, but there is currently no agreed-upon operational definition for …

Objectives To study the frequency of isolated (ie, single-domain) cognitive impairments,
domain specific MRI correlates, and its longitudinal development in people with multiple …

Background The heterogeneous nature of cognitive impairment in people with multiple
sclerosis (PwMS) hampers understanding of the underlying mechanisms and developing …

Multiple sclerosis (MS) is a neurological chronic disease with autoimmune demyelinating
lesions and one of the most common disability causes in young adults. People with MS …