Despite the rising global incidence of central nervous system (CNS) disorders, CNS drug
development remains challenging, with high costs, long pathways to clinical use and high …

Trauma can affect any individual at any location and at any time over a lifespan. The
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …

Background Traumatic brain injury (TBI) is a leading cause of death and disability
worldwide. Microglial/macrophage activation and neuroinflammation are key cellular events …

We tested a newly described molecular memory system, CCR5 signaling, for its role in
recovery after stroke and traumatic brain injury (TBI). CCR5 is uniquely expressed in cortical …

Aims Ferroptosis, a new form of iron‐dependent programmed cell death, has been shown to
be involved in a range of diseases. However, the role of ferroptosis in traumatic brain injury …

The p75 neurotrophin receptor (p75 NTR) functions at the molecular nexus of cell death,
survival, and differentiation. In addition to its contribution to neurodegenerative diseases and …

While popular belief harbors little doubt that perceived stress can cause hair loss and
premature graying, the scientific evidence for this is arguably much thinner. Here, we …

Objective To investigate the prognostic value of inflammatory markers, including
neutrophil/lymphocyte ratio (NLR), derived neutrophil/lymphocyte ratio (dNLR) …

Aim We aimed to investigate the regulatory role of Netrin‐1 (NTN1) in ferroptosis after
traumatic brain injury (TBI) in mice. Methods We assessed the expression pattern of NTN1 …

Polytraumatic injuries, specifically long bone fracture and traumatic brain injury (TBI),
frequently occur together. Clinical observation has long held that TBI can accelerate fracture …