Nanoclays in medicine: a new frontier of an ancient medical practice

KS Katti, H Jasuja, SV Jaswandkar, S Mohanty… - Materials …, 2022 - pubs.rsc.org
Clays have been used as early as 2500 BC in human civilization for medicinal purposes.
The ease of availability, biocompatibility, and versatility of these unique charged 2D …

In vitro veritas: from 2D cultures to organ-on-a-chip models to study immunogenic cell death in the tumor microenvironment

DV Krysko, R Demuynck, I Efimova, F Naessens… - Cells, 2022 - mdpi.com
Immunogenic cell death (ICD) is a functionally unique form of cell death that promotes a T-
cell-dependent anti-tumor immune response specific to antigens originating from dying …

RBM3 suppresses stemness remodeling of prostate cancer in bone microenvironment by modulating N6-methyladenosine on CTNNB1 mRNA

S Zhang, C Lv, Y Niu, C Li, X Li, Y Shang… - Cell Death & …, 2023 - nature.com
Bone metastasis is the most happened metastatic event in prostate cancer (PCa) and needs
a large effort in treatment. When PCa metastasizes to the bone, the new microenvironment …

[HTML][HTML] Prostate cancer bone metastases biology and clinical management

E Archer Goode, N Wang… - Oncology Letters, 2023 - spandidos-publications.com
Prostate cancer (PCa) is one of the most prominent causes of cancer‑related mortality in the
male population. A highly impactful prognostic factor for patients diagnosed with PCa is the …

Interstitial fluid flow contributes to prostate cancer invasion and migration to bone; study conducted using a novel horizontal flow bioreactor

H Jasuja, SV Jaswandkar, DR Katti, KS Katti - Biofabrication, 2023 - iopscience.iop.org
Prostate cancer bone metastasis is the leading cause of cancer-related mortality in men in
the United States, causing severe damage to skeletal tissue. The treatment of advanced …

[HTML][HTML] Control of hydrostatic pressure and osmotic stress in 3D cell culture for mechanobiological studies

AP Kourouklis, A Wahlsten, A Stracuzzi, A Martyts… - Biomaterials …, 2023 - Elsevier
Hydrostatic pressure (HP) and osmotic stress (OS) play an important role in various
biological processes, such as cell proliferation and differentiation. In contrast to canonical …

Molecular basis of conformational changes and mechanics of integrins

HK Gaikwad, SV Jaswandkar… - … of the Royal …, 2023 - royalsocietypublishing.org
Integrin, as a mechanotransducer, establishes the mechanical reciprocity between the
extracellular matrix (ECM) and cells at integrin-mediated adhesion sites. This study used …

Current Advances in the Use of Tissue Engineering for Cancer Metastasis Therapeutics

PD Katti, H Jasuja - Polymers, 2024 - mdpi.com
Cancer is a leading cause of death worldwide and results in nearly 10 million deaths each
year. The global economic burden of cancer from 2020 to 2050 is estimated to be USD 25.2 …

From the matrix to the nucleus and back: Mechanobiology in the light of health, pathologies, and regeneration of oral periodontal tissues

MP Dieterle, A Husari, T Steinberg, X Wang… - Biomolecules, 2021 - mdpi.com
Among oral tissues, the periodontium is permanently subjected to mechanical forces
resulting from chewing, mastication, or orthodontic appliances. Molecularly, these …

Fibrin Hydrogels Reinforced by Reactive Microgels for Stimulus‐Triggered Drug Administration

MA Al Enezy‐Ulbrich, T Belthle, H Malyaran, V Kučikas… - Small, 2024 - Wiley Online Library
Tissue engineering is a steadily growing field of research due to its wide‐ranging
applicability in the field of regenerative medicine. Application‐dependent mechanical …