Schizophrenia is associated with alterations in sensory, motor, and cognitive functions that
emerge before psychosis onset; identifying pathogenic processes that can account for this …

The present article is based on the premise that the risk of developing Alzheimer's disease
(AD) from its prodromal phase (mild cognitive impairment; MCI) is higher when adverse …

Background: Evidence suggests that serotonergic psychedelics (eg psilocybin), have rapid-
acting and long-lasting antidepressant effects after a single dose. However, the mechanism …

Membrane fusion during exocytosis is mediated by assemblies of SNARE (soluble NSF-
attachment protein receptor) and SM (Sec1/Munc18-like) proteins. The SNARE/SM proteins …

Biological supramolecular assemblies, such as phospholipid bilayer membranes, have
been used to demonstrate signal processing via short-term synaptic plasticity (STP) in the …

Background Ultrahigh dose-rate radiotherapy (FLASH-RT) affords improvements in the
therapeutic index by minimizing normal tissue toxicities without compromising antitumor …

Personalized treatments are gaining momentum across all fields of medicine. Precision
medicine can be applied to neuromodulatory techniques, in which focused brain stimulation …

The temporal shape of a pulse in transcranial magnetic stimulation (TMS) influences which
neuron populations are activated preferentially as well as the strength and even direction of …

Abstract The North American Prodrome Longitudinal Study (NAPLS) is a consortium of nine
programs focusing on youth at clinical high risk (CHR) for psychosis. Funded by the National …

Background The rapid-acting clinical effects of ketamine as a novel treatment for depression
along with its complex pharmacology have made it a growing research area. One of the key …