Neutrophil dynamics in pulmonary fibrosis: Pathophysiological and therapeutic perspectives

LE Crowley, RA Stockley, DR Thickett… - European …, 2024 - publications.ersnet.org
The shared pathobiological mechanisms driving progressive fibrosis in interstitial lung
diseases (ILDs) remain unclear. Neutrophils, the most common immune cells in the human …

Multicenter assessment of shotgun metagenomics for pathogen detection

D Liu, H Zhou, T Xu, Q Yang, X Mo, D Shi, J Ai… - …, 2021 - thelancet.com
Background Shotgun metagenomics has been used clinically for diagnosing infectious
diseases. However, most technical assessments have been limited to individual sets of …

Sputum biomarkers in IPF: Evidence for raised gene expression and protein level of IGFBP-2, IL-8 and MMP-7

J Guiot, M Henket, JL Corhay, C Moermans, R Louis - PLoS One, 2017 - journals.plos.org
Background Idiopathic pulmonary fibrosis (IPF) is a rare lung disease of unknown origin
leading rapidly to death. This paper addresses the issue of whether sputum induction is a …

[HTML][HTML] L–lysine ameliorates sepsis-induced acute lung injury in a lipopolysaccharide-induced mouse model

Y Zhang, W Yu, D Han, J Meng, H Wang… - Biomedicine & …, 2019 - Elsevier
Sepsis is a severe, life-threatening condition caused primarily by the cellular response to
infection. Sepsis leads to increased tissue damage and mortality in patients in the intensive …

Guidelines of the Polish Respiratory Society for diagnosis and treatment of idiopathic pulmonary fibrosis

WJ Piotrowski, I Bestry, AJ Białas… - Advances in …, 2020 - publicum.umed.lodz.pl
Introduction: This document presents the guidelines of the Polish Respiratory Society
(PTChP, Polskie Towarzystwo Chorób Płuc) for diagnosis and treatment of idiopathic …

The diagnostic value of the bronchoalveolar lavage in interstitial lung diseases

B Efared, G Ebang-Atsame, S Rabiou… - Journal of negative …, 2017 - Springer
Objective Bronchoalveolar lavage (BAL) is a diagnostic tool often used during the
management of interstitial lung diseases (ILD). However, its diagnostic value in …

Macrophage polarization in interstitial lung diseases

P Wojtan, M Mierzejewski, I Osińska… - … European Journal of …, 2016 - termedia.pl
For both, cD40 and cD163, three populations of cells have been specified: small cells with
strong (+++), large cells with weak (+) and cells with no (–) reaction. Due to lack of …

Integrated approach to bronchoalveolar lavage cytology to distinguish interstitial lung diseases

L Bergantini, M d'Alessandro, P Cameli… - European Journal of …, 2021 - Elsevier
Background Broncho-alveolar lavage (BAL) is a safe diagnostic procedure, useful for
differentiating fibrotic lung disorders and for excluding malignancy and infection. A recent …

Flow Cytometric Analysis of Macrophages and Cytokines Profile in the Bronchoalveolar Lavage Fluid in Patients with Lung Cancer

I Kwiecień, E Rutkowska, A Raniszewska… - Cancers, 2023 - mdpi.com
Simple Summary Macrophages are an integral part of the tumor microenvironment, playing
a role in immunoregulation. We investigated the antigenic and cytokine macrophages profile …

Exhaled volatile organic compounds analysis by e-nose can detect idiopathic pulmonary fibrosis

S Dragonieri, G Scioscia, VN Quaranta… - Journal of Breath …, 2020 - iopscience.iop.org
The current diagnostic work-up and monitoring of idiopathic pulmonary fibrosis (IPF) is often
invasive and time consuming. Breath analysis by e-nose technology has shown potential in …