Background Complex traits typically involve diverse biological pathways and are shaped by
numerous genetic and environmental factors. Pregnancy-associated traits and pathologies …

Preterm birth (PTB) is a large public health problem in the United States and worldwide.
There is a clear genetic component to the pathogenesis of PTB, as evidenced by twin …

It has long been challenging to uncover the molecular mechanisms behind striking
morphological innovations such as mammalian pregnancy. We studied the power of a …

Introduction A major issue in the transcriptomic study of spontaneous preterm birth (sPTB) in
humans is the inability to collect healthy control tissue at the same gestational age (GA) to …

Preterm birth, or the delivery of an infant prior to 37 weeks of gestation, is a significant cause
of infant morbidity and mortality. In the last decade, the advent and continued development …

Placental dysfunction is implicated in many pregnancy complications, including
preeclampsia and preterm birth (PTB). While both these syndromes are influenced by …

Latest omic technologies have increased the availability of biological 'big data'. New
research is required into the integration of multiple omic data and clinical data to make …

The development of the omics high-throughput technologies has led to a better
understanding of the molecular basis underlying many physiological and pathological …

Defined as live births prior to the completion of 37 weeks of gestation, preterm birth (PTB)
affects up to 13% of all US deliveries. PTB is one of the largest causes of perinatal morbidity …

Preterm birth, or the delivery of an infant prior to 37 weeks of gestation, is a significant cause
of infant morbidity and mortality. In the last decade, the advent and continued development …