Advancements in the pharmaceutical applications of probiotics: Dosage forms and formulation technology

KC Baral, R Bajracharya, SH Lee… - International journal of …, 2021 - Taylor & Francis
Probiotics have demonstrated their high potential to treat and/or prevent various diseases
including neurodegenerative disorders, cancers, cardiovascular diseases, and inflammatory …

Paving the way for phage therapy using novel drug delivery approaches

T Briot, C Kolenda, T Ferry, M Medina, F Laurent… - Journal of Controlled …, 2022 - Elsevier
Bacterial resistance against antibiotics is an emergent medical issue. The development of
novel therapeutic approaches is urgently needed and, in this context, bacteriophages …

Oral delivery of therapeutic antibodies with a transmucosal polymeric carrier

W Zhu, Y Chao, Q Jin, L Chen, J Shen, J Zhu, Y Chai… - ACS …, 2023 - ACS Publications
Therapeutic proteins are playing increasingly important roles in treating numerous types of
diseases. However, oral administration of proteins, especially large ones (eg, antibodies) …

Folic acid-decorated alginate nanoparticles loaded hydrogel for the oral delivery of diferourylmethane in colorectal cancer

M Abbasi, M Sohail, MU Minhas, A Mahmood… - International Journal of …, 2023 - Elsevier
The disease-related suffering in colorectal cancer remains prevalent despite advancements
in the field of drug delivery. Chemotherapy-related side effects and non-specificity remain a …

Antibiofilm activity of ultra-small gold nanoclusters against Fusobacterium nucleatum in dental plaque biofilms

Y Zhang, R Chen, Y Wang, P Wang, J Pu, X Xu… - Journal of …, 2022 - Springer
Pathogenic dental plaque biofilms are universal and harmful, which can result in oral
infections and systemic diseases. Many conventional therapeutic methods have proven …

Recent progress of micro/nanomotors to overcome physiological barriers in the gastrointestinal tract

S Zhang, C Zhu, W Huang, H Liu, M Yang… - Journal of Controlled …, 2023 - Elsevier
Oral administration is a convenient administration route for gastrointestinal disease therapy
with good patient compliance. But the nonspecific distribution of the oral drugs may cause …

Tackling TNF-α in autoinflammatory disorders and autoimmune diseases: from conventional to cutting edge in biologics and RNA-based nanomedicines

V Andretto, S Dusi, S Zilio, M Repellin, D Kryza… - Advanced Drug Delivery …, 2023 - Elsevier
Autoinflammatory disorders and autoimmune diseases result from abnormal deviations of
innate and adaptive immunity that heterogeneously affect organs and clinical phenotypes …

Nanocarriers for oral delivery of biologics: small carriers for big payloads

Y Cao, P Rewatkar, R Wang, SZ Hasnain… - Trends in …, 2021 - cell.com
Macromolecular therapeutics of biological origin, also known as biologics, have become
one of the fastest-growing classes of drugs for management of a range of chronic and acute …

Suspended bubble microcapsule delivery systems from droplet microfluidic technology for the local treatment of gastric cancer

X Chen, D Liang, W Sun, X Shou, L Shang… - Chemical Engineering …, 2023 - Elsevier
Microcapsules are promising drug carriers for disease treatment. Specifically, for drug
delivery in the stomach, a key point is to enable retention of the carriers regardless of gastric …

Understanding the journey of biopolymeric nanoformulations for oral drug delivery: Conventional to advanced treatment approaches

A Sharma, N Jangra, D Dheer, SK Jha, G Gupta… - European Polymer …, 2024 - Elsevier
The oral route of drug administration offers a convenient, cost-efficient, and non-invasive
means of administering medications. Nevertheless, as newly developed active …