Clinical trials evaluating medicines, medical devices, and procedures now commonly
assess the economic value of these interventions. The growing number of prospective …

Microsimulation models are becoming increasingly common in the field of decision
modeling for health. Because microsimulation models are computationally more demanding …

Objective: To perform the first randomized controlled trial to compare laparoscopic and open
liver resection. Summary Background Data: Laparoscopic liver resection is increasingly …

Background After a single-center trial and observational studies suggesting that early, goal-
directed therapy (EGDT) reduced mortality from septic shock, three multicenter trials …

Background & Aims Infliximab, a tumor necrosis factor antagonist, is effective for treating
patients with Crohn's disease (CD) and ulcerative colitis (UC). We aimed to determine …

Background Most patients with hip fractures are characterised by older age (> 70 years),
frailty, and functional deterioration, and their long-term outcomes are poor with increased …

Background Manipulation under anaesthesia and arthroscopic capsular release are costly
and invasive treatments for frozen shoulder, but their effectiveness remains uncertain. We …

Background The prevalence of male obesity is increasing but few men take part in weight
loss programmes. We assessed the effect of a weight loss and healthy living programme on …

Objective To examine the costs and cost effectiveness of telehealth in addition to standard
support and treatment, compared with standard support and treatment. Design Economic …

BACKGROUND Lung cancer is the leading cause of cancer death. Surgery remains the
main method of managing early-stage disease. Minimal-access video-assisted …