随着经济高速发展和工业化进程的加速, 生活方式的改变和老龄化进程的加速,
使我国糖尿病的患病率正呈快速上升的趋势, 成为继心脑血管疾病, 肿瘤之后另一个严重危害 …

Hypoglycaemia is a frequent adverse effect of treatment of diabetes mellitus with insulin and
sulphonylureas. Fear of hypoglycaemia alters self-management of diabetes mellitus and …

To achieve good metabolic control in diabetes and keep long term, a combination of
changes in lifestyle and pharmacological treatment is necessary. Achieving near-normal …

OBJECTIVE Insulin delivery methods, glucose-monitoring modalities, and related outcomes
were examined in a large, international, diverse cohort of children and adolescents with type …

Type 1 diabetes accounts for only about 5–10% of all cases of diabetes; however, its
incidence continues to increase worldwide and it has serious short-term and long-term …

To mimic native insulin activity, materials have been developed that encapsulate insulin,
glucose oxidase, and catalase for glucose-responsive insulin delivery. A major challenge …

Background Evidence supporting the addition of specific insulin regimens to oral therapy in
patients with type 2 diabetes mellitus is limited. Methods In this 3-year open-label …

Background Clinical guidelines differ regarding their recommended blood glucose targets
for patients with type 1 diabetes and recent studies on patients with type 2 diabetes suggest …

Aims We compared the effects of continuous subcutaneous insulin infusion (CSII) with those
of multiple daily insulin (MDI) injections on glycaemic control, risk of hypoglycaemic …

Hypoglycemia caused by treatment with a sulfonylurea, a glinide, or insulin coupled with
compromised defenses against the resulting falling plasma glucose concentrations is a …