Insights into glomerular filtration and albuminuria

T Benzing, D Salant - New England Journal of Medicine, 2021 - Mass Medical Soc
Glomerular Filtration and Albuminuria Chronic kidney diseases generally arise from a
disordered kidney filtration barrier within glomeruli. This review describes the roles of …

Primary membranous nephropathy

WG Couser - Clinical Journal of the American Society of …, 2017 - journals.lww.com
Membranous nephropathy (MN) is a unique glomerular lesion that is the most common
cause of idiopathic nephrotic syndrome in nondiabetic white adults. About 80% of cases are …

Antibodies against the node of Ranvier: a real-life evaluation of incidence, clinical features and response to treatment based on a prospective analysis of 1500 sera

E Delmont, A Brodovitch, L Kouton, T Allou… - Journal of …, 2020 - Springer
Introduction IgG4 antibodies against neurofascin (Nfasc155 and Nfasc140/186), contactin
(CNTN1) and contactin-associated protein (Caspr1) are described in specific subtypes of …

PLA2R and THSD7A: disparate paths to the same disease?

LH Beck Jr - Journal of the American Society of Nephrology, 2017 - journals.lww.com
The phospholipase A2 receptor (PLA2R) and thrombospondin type-1 domain-containing 7A
(THSD7A) are the two major autoantigens in primary membranous nephropathy (MN), and …

Detection of PLA2R autoantibodies before the diagnosis of membranous nephropathy

PD Burbelo, M Joshi, A Chaturvedi… - Journal of the …, 2020 - journals.lww.com
Background Circulating serum autoantibodies against the M-type phospholipase A2
receptor (PLA2R-AB) are a key biomarker in the diagnosis and monitoring of primary …

Circulating antibodies against thrombospondin type-I domain-containing 7A in Chinese patients with idiopathic membranous nephropathy

J Wang, Z Cui, J Lu, C Probst, Y Zhang… - Clinical Journal of the …, 2017 - journals.lww.com
Results Among the 578 patients with idiopathic membranous nephropathy, 12 (2%) patients
were identified as THSD7A-positive: ten patients were THSD7A-positive alone, which …

Single-cell profiling reveals transcriptional signatures and cell-cell crosstalk in anti-PLA2R positive idiopathic membranous nephropathy patients

J Xu, C Shen, W Lin, T Meng, JD Ooi… - Frontiers in …, 2021 - frontiersin.org
Idiopathic membranous nephropathy (IMN) is an organ-specific autoimmune disease of the
kidney glomerulus. It may gradually progress to end-stage renal disease (ESRD) …

The tissue proteome in the multi-omic landscape of kidney disease

MM Rinschen, J Saez-Rodriguez - Nature Reviews Nephrology, 2021 - nature.com
Kidney research is entering an era of 'big data'and molecular omics data can provide
comprehensive insights into the molecular footprints of cells. In contrast to transcriptomics …

Chronic inflammatory demyelinating polyneuropathy with concurrent membranous nephropathy: an anti-paranode and podocyte protein antibody study and literature …

Y Hashimoto, H Ogata, R Yamasaki, T Sasaguri… - Frontiers in …, 2018 - frontiersin.org
Background: Several case reports have described the concurrence of chronic inflammatory
demyelinating polyneuropathy (CIDP) and membranous nephropathy (MN). The presence of …

[HTML][HTML] Lupus nephritis: Redefining the treatment goals

AS De Vriese, S Sethi, FC Fervenza - Kidney international, 2025 - Elsevier
The course of proliferative lupus nephritis is characterized by flares of activity alternating
with periods of quiescence against a background of chronic immune dysregulation. An …