Nanoparticles for oral delivery: Design, evaluation and state-of-the-art

AA Date, J Hanes, LM Ensign - Journal of Controlled Release, 2016 - Elsevier
The oral route is a preferred method of drug administration, though achieving effective drug
delivery and minimizing off-target side effects is often challenging. Formulation into …

Pathogenesis of human diffusely adhering Escherichia coli expressing Afa/Dr adhesins (Afa/Dr DAEC): current insights and future challenges

AL Servin - Clinical microbiology reviews, 2014 - Am Soc Microbiol
The pathogenicity and clinical pertinence of diffusely adhering Escherichia coli expressing
the Afa/Dr adhesins (Afa/Dr DAEC) in urinary tract infections (UTIs) and pregnancy …

Pathogenesis of human enterovirulent bacteria: lessons from cultured, fully differentiated human colon cancer cell lines

V Liévin-Le Moal, AL Servin - Microbiology and Molecular Biology …, 2013 - Am Soc Microbiol
Hosts are protected from attack by potentially harmful enteric microorganisms, viruses, and
parasites by the polarized fully differentiated epithelial cells that make up the epithelium …

The Game for Three: Salmonella–Host–Microbiota Interaction Models

K Grzymajlo - Frontiers in Microbiology, 2022 - frontiersin.org
Colonization of the gastrointestinal (GI) tract by enteric pathogens occurs in a context
strongly determined by host-specific gut microbiota, which can significantly affect the …

Intestinal organoid as an in vitro model in studying host-microbial interactions

J Sun - Frontiers in biology, 2017 - Springer
Background Organoid is an in vitro three-dimensional organ-bud that shows realistic
microanatomy and physiological relevance. The progress in generating organoids that …

Differential invasiveness & expression of antimicrobial peptides in Shigella serotypes

C Narayan, V Kant, JK Mahajan… - Indian Journal of …, 2023 - journals.lww.com
Methods: IVOC explants were inoculated with 10 9 colony forming units of different
serotypes of Shigella and recovery of bacteria studied. Histopathological analysis was …

Development of a 3D printed device to support long term intestinal culture as an alternative to hyperoxic chamber methods

MO Costa, R Nosach, JCS Harding - 3D Printing in Medicine, 2017 - Springer
Background Most interactions between pathogenic microorganisms and their target host
occur on mucosal surfaces of internal organs such as the intestine. In vitro organ culture …

Investigating the influence of commensal Limosilactobacillus reuteri and Ruminococcus gnavus on infection with enteropathogenic Escherichia coli in a microaerobic …

C Mcgrath - 2022 - ueaeprints.uea.ac.uk
The gut microbiota has an important role in maintaining intestinal health and protecting
against enteric infections (colonisation resistance). Nevertheless, most of these interactions …

[PDF][PDF] Nutritional intervention in animals: benchmarking of strategies, monitoring biomarkers and immune competence

MM Van Krimpen, MM Hulst, J Van der Meulen… - 2014 - edepot.wur.nl
UK The current study covers a review of literature regarding a number of topics related to
immune competence in farm animals, which are introduced in chapter 1. These topics are: …

Intestinal organoids in studying host− bacterial interactions

J Sun - Organoids and Mini-Organs, 2018 - Elsevier
Researchers have developed various experimental models in vitro and in vivo to investigate
the dynamics of interactions between bacteria and their hosts. Intestinal organoids are three …