Arginine methylation is a common post-translational modification functioning as an
epigenetic regulator of transcription and playing key roles in pre-mRNA splicing, DNA …

As a predominant type II protein arginine methyltransferase, PRMT5 plays critical roles in
various normal cellular processes by catalyzing the mono-and symmetrical dimethylation of …

Many key cellular processes can be regulated by the seemingly simple addition of one, or
two, methyl groups to arginine residues by the nine known mammalian protein arginine …

Protein arginine methyltransferases (PRMTs) catalyze the methyl transfer to the arginine
residues of protein substrates and are classified into three major types based on the final …

Introduction: Arginine methylation is an abundant posttranslational modification occurring in
mammalian cells and catalyzed by protein arginine methyltransferases (PRMTs) …

In response to DNA damage, cells have developed a sophisticated signaling pathway,
consisting of DNA damage sensors, transducers, and effectors, to ensure efficient and …

Histone methylation plays an important regulatory role in chromatin restructuring and RNA
transcription. Arginine methylation that is enzymatically catalyzed by the family of protein …

Proper protein arginine methylation by protein arginine methyltransferase 1 (PRMT1) is
critical for maintaining cellular health, while dysregulation is often associated with disease …

Protein arginine methyltransferase (PRMT) enzymes play a crucial role in RNA splicing,
DNA damage repair, cell signaling, and differentiation. Arginine methylation is a prominent …

Among the nine mammalian protein arginine methyltransferases (PRMTs), PRMT8 is
unusual because it has restricted expression in the nervous system and is the only …