Functional correlates of the lateral and medial entorhinal cortex: objects, path integration and local–global reference frames
JJ Knierim, JP Neunuebel… - … Transactions of the …, 2014 - royalsocietypublishing.org
The hippocampus receives its major cortical input from the medial entorhinal cortex (MEC)
and the lateral entorhinal cortex (LEC). It is commonly believed that the MEC provides …
and the lateral entorhinal cortex (LEC). It is commonly believed that the MEC provides …
Tracking the flow of hippocampal computation: Pattern separation, pattern completion, and attractor dynamics
JJ Knierim, JP Neunuebel - Neurobiology of learning and memory, 2016 - Elsevier
Classic computational theories of the mnemonic functions of the hippocampus ascribe the
processes of pattern separation to the dentate gyrus (DG) and pattern completion to the CA3 …
processes of pattern separation to the dentate gyrus (DG) and pattern completion to the CA3 …
Constant sub-second cycling between representations of possible futures in the hippocampus
Cognitive faculties such as imagination, planning, and decision-making entail the ability to
represent hypothetical experience. Crucially, animal behavior in natural settings implies that …
represent hypothetical experience. Crucially, animal behavior in natural settings implies that …
[HTML][HTML] Disrupted place cell remapping and impaired grid cells in a knockin model of Alzheimer's disease
Patients with Alzheimer's disease (AD) suffer from spatial memory impairment and
wandering behavior, but the brain circuit mechanisms causing such symptoms remain …
wandering behavior, but the brain circuit mechanisms causing such symptoms remain …
A 4 Hz oscillation adaptively synchronizes prefrontal, VTA, and hippocampal activities
S Fujisawa, G Buzsáki - Neuron, 2011 - cell.com
Network oscillations support transient communication across brain structures. We show
here, in rats, that task-related neuronal activity in the medial prefrontal cortex (PFC), the …
here, in rats, that task-related neuronal activity in the medial prefrontal cortex (PFC), the …
Representation of non-spatial and spatial information in the lateral entorhinal cortex
SS Deshmukh, JJ Knierim - Frontiers in behavioral neuroscience, 2011 - frontiersin.org
Some theories of memory propose that the hippocampus integrates the individual items and
events of experience within a contextual or spatial framework. The hippocampus receives …
events of experience within a contextual or spatial framework. The hippocampus receives …
Grid cells without theta oscillations in the entorhinal cortex of bats
MM Yartsev, MP Witter, N Ulanovsky - Nature, 2011 - nature.com
Grid cells provide a neural representation of space, by discharging when an animal
traverses through the vertices of a periodic hexagonal grid spanning the environment …
traverses through the vertices of a periodic hexagonal grid spanning the environment …
Reduction of theta rhythm dissociates grid cell spatial periodicity from directional tuning
Grid cells recorded in the medial entorhinal cortex of freely moving rats exhibit firing at
regular spatial locations and temporal modulation with theta rhythm oscillations (4 to 11 …
regular spatial locations and temporal modulation with theta rhythm oscillations (4 to 11 …
Theta rhythm and the encoding and retrieval of space and time
ME Hasselmo, CE Stern - Neuroimage, 2014 - Elsevier
Physiological data demonstrates theta frequency oscillations associated with memory
function and spatial behavior. Modeling and data from animals provide a perspective on the …
function and spatial behavior. Modeling and data from animals provide a perspective on the …
Multiple time-scales of decision-making in the hippocampus and prefrontal cortex
The prefrontal cortex and hippocampus are crucial for memory-guided decision-making.
Neural activity in the hippocampus exhibits place-cell sequences at multiple timescales …
Neural activity in the hippocampus exhibits place-cell sequences at multiple timescales …