Background Cancer associated with smoking and drinking remains a serious health
problem worldwide. The survival of patients is very poor due to the lack of effective early …

Biobanks are not-for-profit services for the collection, processing, storage and distribution of
biological samples and data for research and diagnostic purposes. In dentistry, biological …

Purpose: Head and neck squamous cell carcinoma (HNSCC) is one of the 10 most common
cancers with a 50% five-year survival rate, which has remained unchanged for the past three …

Emerging biological and translational insights from large sequencing efforts underscore the
need for genetically-relevant cell lines to study the relationships between genomic …

Arecoline, the major alkaloid of areca nut, is known to induce oral carcinogenesis, however,
its mechanism is still needed to elucidate. This study investigated the effects of arecoline on …

Abstract Background The CXCR4-RhoA and PI3K-mTOR signaling pathways play crucial
roles in the dissemination and tumorigenesis of oral squamous cell carcinoma (OSCC) …

Objective Lack of effective therapies remains a problem in the treatment of oral squamous
cell carcinoma (OSCC), especially in patients with advanced tumors. OSCC development is …

Cultured cell lines have played an integral role in the study of tumor biology since the early
1900's. The purpose of this study is to evaluate colorectal cancer (CRC) cell lines with …

Purpose Oral squamous cell carcinoma (OSCC) is a challenging disease to treat. Up to 50%
of OSCC patients with advanced disease develop recurrences. Elucidation of key molecular …

Oral tongue squamous cell carcinoma (OTSCC) is one of the major causes of fatality in India
due to very high percentage of patients with habits of smoking and chewing tobacco and …